The role and uses of antibodies in COVID-19 infections: a living review

Coronavirus disease 2019 has generated a rapidly evolving field of research, with the global scientific community striving for solutions to the current pandemic. Characterizing humoral responses towards SARS-CoV-2, as well as closely related strains, will help determine whether antibodies are centra...

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Autores principales: Scourfield, D Oliver, Reed, Sophie G, Quastel, Max, Alderson, Jennifer, Bart, Valentina M T, Teijeira Crespo, Alicia, Jones, Ruth, Pring, Ellie, Richter, Felix Clemens, Burnell, Stephanie E A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7928637/
https://www.ncbi.nlm.nih.gov/pubmed/34192270
http://dx.doi.org/10.1093/oxfimm/iqab003
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author Scourfield, D Oliver
Reed, Sophie G
Quastel, Max
Alderson, Jennifer
Bart, Valentina M T
Teijeira Crespo, Alicia
Jones, Ruth
Pring, Ellie
Richter, Felix Clemens
Burnell, Stephanie E A
author_facet Scourfield, D Oliver
Reed, Sophie G
Quastel, Max
Alderson, Jennifer
Bart, Valentina M T
Teijeira Crespo, Alicia
Jones, Ruth
Pring, Ellie
Richter, Felix Clemens
Burnell, Stephanie E A
author_sort Scourfield, D Oliver
collection PubMed
description Coronavirus disease 2019 has generated a rapidly evolving field of research, with the global scientific community striving for solutions to the current pandemic. Characterizing humoral responses towards SARS-CoV-2, as well as closely related strains, will help determine whether antibodies are central to infection control, and aid the design of therapeutics and vaccine candidates. This review outlines the major aspects of SARS-CoV-2-specific antibody research to date, with a focus on the various prophylactic and therapeutic uses of antibodies to alleviate disease in addition to the potential of cross-reactive therapies and the implications of long-term immunity.
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spelling pubmed-79286372021-03-04 The role and uses of antibodies in COVID-19 infections: a living review Scourfield, D Oliver Reed, Sophie G Quastel, Max Alderson, Jennifer Bart, Valentina M T Teijeira Crespo, Alicia Jones, Ruth Pring, Ellie Richter, Felix Clemens Burnell, Stephanie E A Oxf Open Immunol Review Article Coronavirus disease 2019 has generated a rapidly evolving field of research, with the global scientific community striving for solutions to the current pandemic. Characterizing humoral responses towards SARS-CoV-2, as well as closely related strains, will help determine whether antibodies are central to infection control, and aid the design of therapeutics and vaccine candidates. This review outlines the major aspects of SARS-CoV-2-specific antibody research to date, with a focus on the various prophylactic and therapeutic uses of antibodies to alleviate disease in addition to the potential of cross-reactive therapies and the implications of long-term immunity. Oxford University Press 2021-01-28 /pmc/articles/PMC7928637/ /pubmed/34192270 http://dx.doi.org/10.1093/oxfimm/iqab003 Text en © The Author(s) 2021. Published by Oxford University Press. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Scourfield, D Oliver
Reed, Sophie G
Quastel, Max
Alderson, Jennifer
Bart, Valentina M T
Teijeira Crespo, Alicia
Jones, Ruth
Pring, Ellie
Richter, Felix Clemens
Burnell, Stephanie E A
The role and uses of antibodies in COVID-19 infections: a living review
title The role and uses of antibodies in COVID-19 infections: a living review
title_full The role and uses of antibodies in COVID-19 infections: a living review
title_fullStr The role and uses of antibodies in COVID-19 infections: a living review
title_full_unstemmed The role and uses of antibodies in COVID-19 infections: a living review
title_short The role and uses of antibodies in COVID-19 infections: a living review
title_sort role and uses of antibodies in covid-19 infections: a living review
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7928637/
https://www.ncbi.nlm.nih.gov/pubmed/34192270
http://dx.doi.org/10.1093/oxfimm/iqab003
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