Mosaic nanoparticles elicit cross-reactive immune responses to zoonotic coronaviruses in mice

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Protection against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and SARS-related emergent zoonotic coronaviruses is urgently needed. We made homotypic nanoparticles displaying the receptor binding domain (RBD) of SARS-CoV-2 or co-displaying SARS-CoV-2 RBD along with RBDs from animal...

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Detalles Bibliográficos
Autores principales: Cohen, Alexander A., Gnanapragasam, Priyanthi N. P., Lee, Yu E., Hoffman, Pauline R., Ou, Susan, Kakutani, Leesa M., Keeffe, Jennifer R., Wu, Hung-Jen, Howarth, Mark, West, Anthony P., Barnes, Christopher O., Nussenzweig, Michel C., Bjorkman, Pamela J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
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Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7928838/
https://www.ncbi.nlm.nih.gov/pubmed/33436524
http://dx.doi.org/10.1126/science.abf6840
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