Cargando…

Projected HIV and Bacterial Sexually Transmitted Infection Incidence Following COVID-19–Related Sexual Distancing and Clinical Service Interruption

BACKGROUND: The global COVID-19 pandemic has the potential to indirectly impact transmission dynamics and prevention of HIV and other sexually transmitted infections (STI). It is unknown what combined impact reductions in sexual activity and interruptions in HIV/STI services will have on HIV/STI epi...

Descripción completa

Detalles Bibliográficos
Autores principales: Jenness, Samuel M, Le Guillou, Adrien, Chandra, Christina, Mann, Laura M, Sanchez, Travis, Westreich, Daniel, Marcus, Julia L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7928867/
https://www.ncbi.nlm.nih.gov/pubmed/33507308
http://dx.doi.org/10.1093/infdis/jiab051
_version_ 1783659900287582208
author Jenness, Samuel M
Le Guillou, Adrien
Chandra, Christina
Mann, Laura M
Sanchez, Travis
Westreich, Daniel
Marcus, Julia L
author_facet Jenness, Samuel M
Le Guillou, Adrien
Chandra, Christina
Mann, Laura M
Sanchez, Travis
Westreich, Daniel
Marcus, Julia L
author_sort Jenness, Samuel M
collection PubMed
description BACKGROUND: The global COVID-19 pandemic has the potential to indirectly impact transmission dynamics and prevention of HIV and other sexually transmitted infections (STI). It is unknown what combined impact reductions in sexual activity and interruptions in HIV/STI services will have on HIV/STI epidemic trajectories. METHODS: We adapted a model of HIV, gonorrhea, and chlamydia for a population of approximately 103 000 men who have sex with men (MSM) in the Atlanta area. Model scenarios varied the timing, overlap, and relative extent of COVID-19–related sexual distancing and service interruption within 4 service categories (HIV screening, preexposure prophylaxis, antiretroviral therapy, and STI treatment). RESULTS: A 50% relative decrease in sexual partnerships and interruption of all clinical services, both lasting 18 months, would generally offset each other for HIV (total 5-year population impact for Atlanta MSM, −227 cases), but have net protective effect for STIs (−23 800 cases). If distancing lasted only 3 months but service interruption lasted 18 months, the total 5-year population impact would be an additional 890 HIV cases and 57 500 STI cases. CONCLUSIONS: Immediate action to limit the impact of service interruptions is needed to address the indirect effects of the global COVID-19 pandemic on the HIV/STI epidemic.
format Online
Article
Text
id pubmed-7928867
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Oxford University Press
record_format MEDLINE/PubMed
spelling pubmed-79288672021-03-04 Projected HIV and Bacterial Sexually Transmitted Infection Incidence Following COVID-19–Related Sexual Distancing and Clinical Service Interruption Jenness, Samuel M Le Guillou, Adrien Chandra, Christina Mann, Laura M Sanchez, Travis Westreich, Daniel Marcus, Julia L J Infect Dis Major Articles and Brief Reports BACKGROUND: The global COVID-19 pandemic has the potential to indirectly impact transmission dynamics and prevention of HIV and other sexually transmitted infections (STI). It is unknown what combined impact reductions in sexual activity and interruptions in HIV/STI services will have on HIV/STI epidemic trajectories. METHODS: We adapted a model of HIV, gonorrhea, and chlamydia for a population of approximately 103 000 men who have sex with men (MSM) in the Atlanta area. Model scenarios varied the timing, overlap, and relative extent of COVID-19–related sexual distancing and service interruption within 4 service categories (HIV screening, preexposure prophylaxis, antiretroviral therapy, and STI treatment). RESULTS: A 50% relative decrease in sexual partnerships and interruption of all clinical services, both lasting 18 months, would generally offset each other for HIV (total 5-year population impact for Atlanta MSM, −227 cases), but have net protective effect for STIs (−23 800 cases). If distancing lasted only 3 months but service interruption lasted 18 months, the total 5-year population impact would be an additional 890 HIV cases and 57 500 STI cases. CONCLUSIONS: Immediate action to limit the impact of service interruptions is needed to address the indirect effects of the global COVID-19 pandemic on the HIV/STI epidemic. Oxford University Press 2021-01-28 /pmc/articles/PMC7928867/ /pubmed/33507308 http://dx.doi.org/10.1093/infdis/jiab051 Text en © The Author(s) 2021. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com. https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model)
spellingShingle Major Articles and Brief Reports
Jenness, Samuel M
Le Guillou, Adrien
Chandra, Christina
Mann, Laura M
Sanchez, Travis
Westreich, Daniel
Marcus, Julia L
Projected HIV and Bacterial Sexually Transmitted Infection Incidence Following COVID-19–Related Sexual Distancing and Clinical Service Interruption
title Projected HIV and Bacterial Sexually Transmitted Infection Incidence Following COVID-19–Related Sexual Distancing and Clinical Service Interruption
title_full Projected HIV and Bacterial Sexually Transmitted Infection Incidence Following COVID-19–Related Sexual Distancing and Clinical Service Interruption
title_fullStr Projected HIV and Bacterial Sexually Transmitted Infection Incidence Following COVID-19–Related Sexual Distancing and Clinical Service Interruption
title_full_unstemmed Projected HIV and Bacterial Sexually Transmitted Infection Incidence Following COVID-19–Related Sexual Distancing and Clinical Service Interruption
title_short Projected HIV and Bacterial Sexually Transmitted Infection Incidence Following COVID-19–Related Sexual Distancing and Clinical Service Interruption
title_sort projected hiv and bacterial sexually transmitted infection incidence following covid-19–related sexual distancing and clinical service interruption
topic Major Articles and Brief Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7928867/
https://www.ncbi.nlm.nih.gov/pubmed/33507308
http://dx.doi.org/10.1093/infdis/jiab051
work_keys_str_mv AT jennesssamuelm projectedhivandbacterialsexuallytransmittedinfectionincidencefollowingcovid19relatedsexualdistancingandclinicalserviceinterruption
AT leguillouadrien projectedhivandbacterialsexuallytransmittedinfectionincidencefollowingcovid19relatedsexualdistancingandclinicalserviceinterruption
AT chandrachristina projectedhivandbacterialsexuallytransmittedinfectionincidencefollowingcovid19relatedsexualdistancingandclinicalserviceinterruption
AT mannlauram projectedhivandbacterialsexuallytransmittedinfectionincidencefollowingcovid19relatedsexualdistancingandclinicalserviceinterruption
AT sancheztravis projectedhivandbacterialsexuallytransmittedinfectionincidencefollowingcovid19relatedsexualdistancingandclinicalserviceinterruption
AT westreichdaniel projectedhivandbacterialsexuallytransmittedinfectionincidencefollowingcovid19relatedsexualdistancingandclinicalserviceinterruption
AT marcusjulial projectedhivandbacterialsexuallytransmittedinfectionincidencefollowingcovid19relatedsexualdistancingandclinicalserviceinterruption