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Cardiac arrest in COVID-19: characteristics and outcomes of in- and out-of-hospital cardiac arrest. A report from the Swedish Registry for Cardiopulmonary Resuscitation

AIM: To study the characteristics and outcome among cardiac arrest cases with COVID-19 and differences between the pre-pandemic and the pandemic period in out-of-hospital cardiac arrest (OHCA) and in-hospital cardiac arrest (IHCA). METHOD AND RESULTS: We included all patients reported to the Swedish...

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Autores principales: Sultanian, Pedram, Lundgren, Peter, Strömsöe, Anneli, Aune, Solveig, Bergström, Göran, Hagberg, Eva, Hollenberg, Jacob, Lindqvist, Jonny, Djärv, Therese, Castelheim, Albert, Thorén, Anna, Hessulf, Fredrik, Svensson, Leif, Claesson, Andreas, Friberg, Hans, Nordberg, Per, Omerovic, Elmir, Rosengren, Annika, Herlitz, Johan, Rawshani, Araz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7928992/
https://www.ncbi.nlm.nih.gov/pubmed/33543259
http://dx.doi.org/10.1093/eurheartj/ehaa1067
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author Sultanian, Pedram
Lundgren, Peter
Strömsöe, Anneli
Aune, Solveig
Bergström, Göran
Hagberg, Eva
Hollenberg, Jacob
Lindqvist, Jonny
Djärv, Therese
Castelheim, Albert
Thorén, Anna
Hessulf, Fredrik
Svensson, Leif
Claesson, Andreas
Friberg, Hans
Nordberg, Per
Omerovic, Elmir
Rosengren, Annika
Herlitz, Johan
Rawshani, Araz
author_facet Sultanian, Pedram
Lundgren, Peter
Strömsöe, Anneli
Aune, Solveig
Bergström, Göran
Hagberg, Eva
Hollenberg, Jacob
Lindqvist, Jonny
Djärv, Therese
Castelheim, Albert
Thorén, Anna
Hessulf, Fredrik
Svensson, Leif
Claesson, Andreas
Friberg, Hans
Nordberg, Per
Omerovic, Elmir
Rosengren, Annika
Herlitz, Johan
Rawshani, Araz
author_sort Sultanian, Pedram
collection PubMed
description AIM: To study the characteristics and outcome among cardiac arrest cases with COVID-19 and differences between the pre-pandemic and the pandemic period in out-of-hospital cardiac arrest (OHCA) and in-hospital cardiac arrest (IHCA). METHOD AND RESULTS: We included all patients reported to the Swedish Registry for Cardiopulmonary Resuscitation from 1 January to 20 July 2020. We defined 16 March 2020 as the start of the pandemic. We assessed overall and 30-day mortality using Cox regression and logistic regression, respectively. We studied 1946 cases of OHCA and 1080 cases of IHCA during the entire period. During the pandemic, 88 (10.0%) of OHCAs and 72 (16.1%) of IHCAs had ongoing COVID-19. With regards to OHCA during the pandemic, the odds ratio for 30-day mortality in COVID-19-positive cases, compared with COVID-19-negative cases, was 3.40 [95% confidence interval (CI) 1.31–11.64]; the corresponding hazard ratio was 1.45 (95% CI 1.13–1.85). Adjusted 30-day survival was 4.7% for patients with COVID-19, 9.8% for patients without COVID-19, and 7.6% in the pre-pandemic period. With regards to IHCA during the pandemic, the odds ratio for COVID-19-positive cases, compared with COVID-19-negative cases, was 2.27 (95% CI 1.27–4.24); the corresponding hazard ratio was 1.48 (95% CI 1.09–2.01). Adjusted 30-day survival was 23.1% in COVID-19-positive cases, 39.5% in patients without COVID-19, and 36.4% in the pre-pandemic period. CONCLUSION: During the pandemic phase, COVID-19 was involved in at least 10% of all OHCAs and 16% of IHCAs, and, among COVID-19 cases, 30-day mortality was increased 3.4-fold in OHCA and 2.3-fold in IHCA.
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spelling pubmed-79289922021-03-04 Cardiac arrest in COVID-19: characteristics and outcomes of in- and out-of-hospital cardiac arrest. A report from the Swedish Registry for Cardiopulmonary Resuscitation Sultanian, Pedram Lundgren, Peter Strömsöe, Anneli Aune, Solveig Bergström, Göran Hagberg, Eva Hollenberg, Jacob Lindqvist, Jonny Djärv, Therese Castelheim, Albert Thorén, Anna Hessulf, Fredrik Svensson, Leif Claesson, Andreas Friberg, Hans Nordberg, Per Omerovic, Elmir Rosengren, Annika Herlitz, Johan Rawshani, Araz Eur Heart J Clnical Research AIM: To study the characteristics and outcome among cardiac arrest cases with COVID-19 and differences between the pre-pandemic and the pandemic period in out-of-hospital cardiac arrest (OHCA) and in-hospital cardiac arrest (IHCA). METHOD AND RESULTS: We included all patients reported to the Swedish Registry for Cardiopulmonary Resuscitation from 1 January to 20 July 2020. We defined 16 March 2020 as the start of the pandemic. We assessed overall and 30-day mortality using Cox regression and logistic regression, respectively. We studied 1946 cases of OHCA and 1080 cases of IHCA during the entire period. During the pandemic, 88 (10.0%) of OHCAs and 72 (16.1%) of IHCAs had ongoing COVID-19. With regards to OHCA during the pandemic, the odds ratio for 30-day mortality in COVID-19-positive cases, compared with COVID-19-negative cases, was 3.40 [95% confidence interval (CI) 1.31–11.64]; the corresponding hazard ratio was 1.45 (95% CI 1.13–1.85). Adjusted 30-day survival was 4.7% for patients with COVID-19, 9.8% for patients without COVID-19, and 7.6% in the pre-pandemic period. With regards to IHCA during the pandemic, the odds ratio for COVID-19-positive cases, compared with COVID-19-negative cases, was 2.27 (95% CI 1.27–4.24); the corresponding hazard ratio was 1.48 (95% CI 1.09–2.01). Adjusted 30-day survival was 23.1% in COVID-19-positive cases, 39.5% in patients without COVID-19, and 36.4% in the pre-pandemic period. CONCLUSION: During the pandemic phase, COVID-19 was involved in at least 10% of all OHCAs and 16% of IHCAs, and, among COVID-19 cases, 30-day mortality was increased 3.4-fold in OHCA and 2.3-fold in IHCA. Oxford University Press 2021-02-05 /pmc/articles/PMC7928992/ /pubmed/33543259 http://dx.doi.org/10.1093/eurheartj/ehaa1067 Text en © The Author(s) 2021. Published by Oxford University Press on behalf of the European Society of Cardiology. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Clnical Research
Sultanian, Pedram
Lundgren, Peter
Strömsöe, Anneli
Aune, Solveig
Bergström, Göran
Hagberg, Eva
Hollenberg, Jacob
Lindqvist, Jonny
Djärv, Therese
Castelheim, Albert
Thorén, Anna
Hessulf, Fredrik
Svensson, Leif
Claesson, Andreas
Friberg, Hans
Nordberg, Per
Omerovic, Elmir
Rosengren, Annika
Herlitz, Johan
Rawshani, Araz
Cardiac arrest in COVID-19: characteristics and outcomes of in- and out-of-hospital cardiac arrest. A report from the Swedish Registry for Cardiopulmonary Resuscitation
title Cardiac arrest in COVID-19: characteristics and outcomes of in- and out-of-hospital cardiac arrest. A report from the Swedish Registry for Cardiopulmonary Resuscitation
title_full Cardiac arrest in COVID-19: characteristics and outcomes of in- and out-of-hospital cardiac arrest. A report from the Swedish Registry for Cardiopulmonary Resuscitation
title_fullStr Cardiac arrest in COVID-19: characteristics and outcomes of in- and out-of-hospital cardiac arrest. A report from the Swedish Registry for Cardiopulmonary Resuscitation
title_full_unstemmed Cardiac arrest in COVID-19: characteristics and outcomes of in- and out-of-hospital cardiac arrest. A report from the Swedish Registry for Cardiopulmonary Resuscitation
title_short Cardiac arrest in COVID-19: characteristics and outcomes of in- and out-of-hospital cardiac arrest. A report from the Swedish Registry for Cardiopulmonary Resuscitation
title_sort cardiac arrest in covid-19: characteristics and outcomes of in- and out-of-hospital cardiac arrest. a report from the swedish registry for cardiopulmonary resuscitation
topic Clnical Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7928992/
https://www.ncbi.nlm.nih.gov/pubmed/33543259
http://dx.doi.org/10.1093/eurheartj/ehaa1067
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