Dopamine activates NF-κB and primes the NLRP3 inflammasome in primary human macrophages

Induction of innate immune genes in the brain is thought to be a major factor in the development of addiction to substances of abuse. As the major component of the innate immune system in the brain, aberrant activation of myeloid cells such as macrophages and microglia due to substance use may media...

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Detalles Bibliográficos
Autores principales: Nolan, R.A., Reeb, K.L., Rong, Y., Matt, S.M., Johnson, H.S., Runner, K., Gaskill, P.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Full Length Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7929492/
https://www.ncbi.nlm.nih.gov/pubmed/33665636
http://dx.doi.org/10.1016/j.bbih.2019.100030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7929492/
https://www.ncbi.nlm.nih.gov/pubmed/33665636
http://dx.doi.org/10.1016/j.bbih.2019.100030

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