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Dopamine activates NF-κB and primes the NLRP3 inflammasome in primary human macrophages
Induction of innate immune genes in the brain is thought to be a major factor in the development of addiction to substances of abuse. As the major component of the innate immune system in the brain, aberrant activation of myeloid cells such as macrophages and microglia due to substance use may media...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7929492/ https://www.ncbi.nlm.nih.gov/pubmed/33665636 http://dx.doi.org/10.1016/j.bbih.2019.100030 |