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α-Synuclein plasma membrane localization correlates with cellular phosphatidylinositol polyphosphate levels
The Parkinson’s disease protein α-synuclein (αSyn) promotes membrane fusion and fission by interacting with various negatively charged phospholipids. Despite postulated roles in endocytosis and exocytosis, plasma membrane (PM) interactions of αSyn are poorly understood. Here, we show that phosphatid...
Autores principales: | Jacob, Reeba Susan, Eichmann, Cédric, Dema, Alessandro, Mercadante, Davide, Selenko, Philipp |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7929559/ https://www.ncbi.nlm.nih.gov/pubmed/33587036 http://dx.doi.org/10.7554/eLife.61951 |
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