Cargando…

Residual Gensini Score Is Associated With Long-Term Cardiac Mortality in Patients With Heart Failure After Percutaneous Coronary Intervention

Background: Coronary revascularization is important in heart failure (HF) with ischemic etiology. Coronary scoring systems are useful to evaluate coronary artery disease, but said systems for residual stenosis after revascularization are still poorly understood. Therefore, the aim of the current stu...

Descripción completa

Detalles Bibliográficos
Autores principales: Yokokawa, Tetsuro, Yoshihisa, Akiomi, Kiko, Takatoyo, Shimizu, Takeshi, Misaka, Tomofumi, Yamaki, Takayoshi, Kunii, Hiroyuki, Nakazato, Kazuhiko, Ishida, Takafumi, Takeishi, Yasuchika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Circulation Society 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7929761/
https://www.ncbi.nlm.nih.gov/pubmed/33693213
http://dx.doi.org/10.1253/circrep.CR-19-0121
_version_ 1783659979207606272
author Yokokawa, Tetsuro
Yoshihisa, Akiomi
Kiko, Takatoyo
Shimizu, Takeshi
Misaka, Tomofumi
Yamaki, Takayoshi
Kunii, Hiroyuki
Nakazato, Kazuhiko
Ishida, Takafumi
Takeishi, Yasuchika
author_facet Yokokawa, Tetsuro
Yoshihisa, Akiomi
Kiko, Takatoyo
Shimizu, Takeshi
Misaka, Tomofumi
Yamaki, Takayoshi
Kunii, Hiroyuki
Nakazato, Kazuhiko
Ishida, Takafumi
Takeishi, Yasuchika
author_sort Yokokawa, Tetsuro
collection PubMed
description Background: Coronary revascularization is important in heart failure (HF) with ischemic etiology. Coronary scoring systems are useful to evaluate coronary artery disease, but said systems for residual stenosis after revascularization are still poorly understood. Therefore, the aim of the current study was to clarify the prognostic impact of residual stenosis using a coronary scoring system, Gensini score, in HF patients after percutaneous coronary intervention (PCI). Methods and Results: We analyzed consecutive hospitalized ischemic HF patients (n=199) who underwent PCI. We calculated residual Gensini score after PCI, and divided the patients into 2 groups based on median residual Gensini score. The patients with high scores (≥10, n=101) had a higher prevalence of anemia, lower prevalence of dyslipidemia, and lower left ventricular ejection fraction, compared with those with low scores (<10, n=98). During the median follow-up period of 1,581 days (range, 20–2,896 days), the high-score patients had a higher cardiac mortality than the low-score group (log rank, P=0.001). Conclusions: In patients with HF after PCI, residual Gensini score was associated with long-term cardiac mortality. Residual Gensini score may be a useful index for risk stratification of HF after PCI.
format Online
Article
Text
id pubmed-7929761
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher The Japanese Circulation Society
record_format MEDLINE/PubMed
spelling pubmed-79297612021-03-09 Residual Gensini Score Is Associated With Long-Term Cardiac Mortality in Patients With Heart Failure After Percutaneous Coronary Intervention Yokokawa, Tetsuro Yoshihisa, Akiomi Kiko, Takatoyo Shimizu, Takeshi Misaka, Tomofumi Yamaki, Takayoshi Kunii, Hiroyuki Nakazato, Kazuhiko Ishida, Takafumi Takeishi, Yasuchika Circ Rep Original article Background: Coronary revascularization is important in heart failure (HF) with ischemic etiology. Coronary scoring systems are useful to evaluate coronary artery disease, but said systems for residual stenosis after revascularization are still poorly understood. Therefore, the aim of the current study was to clarify the prognostic impact of residual stenosis using a coronary scoring system, Gensini score, in HF patients after percutaneous coronary intervention (PCI). Methods and Results: We analyzed consecutive hospitalized ischemic HF patients (n=199) who underwent PCI. We calculated residual Gensini score after PCI, and divided the patients into 2 groups based on median residual Gensini score. The patients with high scores (≥10, n=101) had a higher prevalence of anemia, lower prevalence of dyslipidemia, and lower left ventricular ejection fraction, compared with those with low scores (<10, n=98). During the median follow-up period of 1,581 days (range, 20–2,896 days), the high-score patients had a higher cardiac mortality than the low-score group (log rank, P=0.001). Conclusions: In patients with HF after PCI, residual Gensini score was associated with long-term cardiac mortality. Residual Gensini score may be a useful index for risk stratification of HF after PCI. The Japanese Circulation Society 2020-01-28 /pmc/articles/PMC7929761/ /pubmed/33693213 http://dx.doi.org/10.1253/circrep.CR-19-0121 Text en Copyright © 2020, THE JAPANESE CIRCULATION SOCIETY This article is licensed under a Creative Commons [Attribution-NonCommercial-NoDerivatives 4.0 International] license.https://creativecommons.org/licenses/by-nc-nd/4.0/
spellingShingle Original article
Yokokawa, Tetsuro
Yoshihisa, Akiomi
Kiko, Takatoyo
Shimizu, Takeshi
Misaka, Tomofumi
Yamaki, Takayoshi
Kunii, Hiroyuki
Nakazato, Kazuhiko
Ishida, Takafumi
Takeishi, Yasuchika
Residual Gensini Score Is Associated With Long-Term Cardiac Mortality in Patients With Heart Failure After Percutaneous Coronary Intervention
title Residual Gensini Score Is Associated With Long-Term Cardiac Mortality in Patients With Heart Failure After Percutaneous Coronary Intervention
title_full Residual Gensini Score Is Associated With Long-Term Cardiac Mortality in Patients With Heart Failure After Percutaneous Coronary Intervention
title_fullStr Residual Gensini Score Is Associated With Long-Term Cardiac Mortality in Patients With Heart Failure After Percutaneous Coronary Intervention
title_full_unstemmed Residual Gensini Score Is Associated With Long-Term Cardiac Mortality in Patients With Heart Failure After Percutaneous Coronary Intervention
title_short Residual Gensini Score Is Associated With Long-Term Cardiac Mortality in Patients With Heart Failure After Percutaneous Coronary Intervention
title_sort residual gensini score is associated with long-term cardiac mortality in patients with heart failure after percutaneous coronary intervention
topic Original article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7929761/
https://www.ncbi.nlm.nih.gov/pubmed/33693213
http://dx.doi.org/10.1253/circrep.CR-19-0121
work_keys_str_mv AT yokokawatetsuro residualgensiniscoreisassociatedwithlongtermcardiacmortalityinpatientswithheartfailureafterpercutaneouscoronaryintervention
AT yoshihisaakiomi residualgensiniscoreisassociatedwithlongtermcardiacmortalityinpatientswithheartfailureafterpercutaneouscoronaryintervention
AT kikotakatoyo residualgensiniscoreisassociatedwithlongtermcardiacmortalityinpatientswithheartfailureafterpercutaneouscoronaryintervention
AT shimizutakeshi residualgensiniscoreisassociatedwithlongtermcardiacmortalityinpatientswithheartfailureafterpercutaneouscoronaryintervention
AT misakatomofumi residualgensiniscoreisassociatedwithlongtermcardiacmortalityinpatientswithheartfailureafterpercutaneouscoronaryintervention
AT yamakitakayoshi residualgensiniscoreisassociatedwithlongtermcardiacmortalityinpatientswithheartfailureafterpercutaneouscoronaryintervention
AT kuniihiroyuki residualgensiniscoreisassociatedwithlongtermcardiacmortalityinpatientswithheartfailureafterpercutaneouscoronaryintervention
AT nakazatokazuhiko residualgensiniscoreisassociatedwithlongtermcardiacmortalityinpatientswithheartfailureafterpercutaneouscoronaryintervention
AT ishidatakafumi residualgensiniscoreisassociatedwithlongtermcardiacmortalityinpatientswithheartfailureafterpercutaneouscoronaryintervention
AT takeishiyasuchika residualgensiniscoreisassociatedwithlongtermcardiacmortalityinpatientswithheartfailureafterpercutaneouscoronaryintervention