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The SARS-CoV-2 receptor-binding domain preferentially recognizes blood group A
The RBD of SARS-CoV-2 shares sequence similarity with an ancient lectin family known to bind blood group antigens. SARS-CoV-2 RBD binds the blood group A expressed on respiratory epithelial cells, directly linking blood group A and SARS-CoV-2.
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society of Hematology
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7929867/ https://www.ncbi.nlm.nih.gov/pubmed/33656534 http://dx.doi.org/10.1182/bloodadvances.2020003259 |
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| author | Wu, Shang-Chuen Arthur, Connie M. Wang, Jianmei Verkerke, Hans Josephson, Cassandra D. Kalman, Daniel Roback, John D. Cummings, Richard D. Stowell, Sean R. |
| author_facet | Wu, Shang-Chuen Arthur, Connie M. Wang, Jianmei Verkerke, Hans Josephson, Cassandra D. Kalman, Daniel Roback, John D. Cummings, Richard D. Stowell, Sean R. |
| author_sort | Wu, Shang-Chuen |
| collection | PubMed |
| description | The RBD of SARS-CoV-2 shares sequence similarity with an ancient lectin family known to bind blood group antigens. SARS-CoV-2 RBD binds the blood group A expressed on respiratory epithelial cells, directly linking blood group A and SARS-CoV-2. |
| format | Online Article Text |
| id | pubmed-7929867 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2021 |
| publisher | American Society of Hematology |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-79298672021-03-04 The SARS-CoV-2 receptor-binding domain preferentially recognizes blood group A Wu, Shang-Chuen Arthur, Connie M. Wang, Jianmei Verkerke, Hans Josephson, Cassandra D. Kalman, Daniel Roback, John D. Cummings, Richard D. Stowell, Sean R. Blood Adv Stimulus Report The RBD of SARS-CoV-2 shares sequence similarity with an ancient lectin family known to bind blood group antigens. SARS-CoV-2 RBD binds the blood group A expressed on respiratory epithelial cells, directly linking blood group A and SARS-CoV-2. American Society of Hematology 2021-03-03 /pmc/articles/PMC7929867/ /pubmed/33656534 http://dx.doi.org/10.1182/bloodadvances.2020003259 Text en © 2021 by The American Society of Hematology This article is made available via the PMC Open Access Subset for unrestricted reuse and analyses in any form or by any means with acknowledgment of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic or until permissions are revoked in writing. Upon expiration of these permissions, PMC is granted a perpetual license to make this article available via PMC and Europe PMC, consistent with existing copyright protections. |
| spellingShingle | Stimulus Report Wu, Shang-Chuen Arthur, Connie M. Wang, Jianmei Verkerke, Hans Josephson, Cassandra D. Kalman, Daniel Roback, John D. Cummings, Richard D. Stowell, Sean R. The SARS-CoV-2 receptor-binding domain preferentially recognizes blood group A |
| title | The SARS-CoV-2 receptor-binding domain preferentially recognizes blood group A |
| title_full | The SARS-CoV-2 receptor-binding domain preferentially recognizes blood group A |
| title_fullStr | The SARS-CoV-2 receptor-binding domain preferentially recognizes blood group A |
| title_full_unstemmed | The SARS-CoV-2 receptor-binding domain preferentially recognizes blood group A |
| title_short | The SARS-CoV-2 receptor-binding domain preferentially recognizes blood group A |
| title_sort | sars-cov-2 receptor-binding domain preferentially recognizes blood group a |
| topic | Stimulus Report |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7929867/ https://www.ncbi.nlm.nih.gov/pubmed/33656534 http://dx.doi.org/10.1182/bloodadvances.2020003259 |
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