Circulating prostate cancer cells have differential resistance to fluid shear stress-induced cell death

Circulating tumor cells (CTCs) are exposed to fluid shear stress (FSS) of greater than 1000 dyn/cm(2) (100 Pa) in circulation. Normally, CTCs that are exposed to FSS of this magnitude die. However, some CTCs develop resistance to this FSS, allowing them to colonize distant organs. We explored how pr...

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Detalles Bibliográficos
Autores principales: Hope, Jacob M., Bersi, Matthew R., Dombroski, Jenna A., Clinch, Andrea B., Pereles, Rebecca S., Merryman, W. David, King, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7929932/
https://www.ncbi.nlm.nih.gov/pubmed/33526716
http://dx.doi.org/10.1242/jcs.251470

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