Germ granule dysfunction is a hallmark and mirror of Piwi mutant sterility

In several species, Piwi/piRNA genome silencing defects cause immediate sterility that correlates with transposon expression and transposon-induced genomic instability. In C. elegans, mutations in the Piwi-related gene (prg-1) and other piRNA deficient mutants cause a transgenerational decline in fe...

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Detalles Bibliográficos
Autores principales: Spichal, Maya, Heestand, Bree, Billmyre, Katherine Kretovich, Frenk, Stephen, Mello, Craig C., Ahmed, Shawn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7930041/
https://www.ncbi.nlm.nih.gov/pubmed/33658512
http://dx.doi.org/10.1038/s41467-021-21635-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7930041/
https://www.ncbi.nlm.nih.gov/pubmed/33658512
http://dx.doi.org/10.1038/s41467-021-21635-0

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