Utilizing Computational Machine Learning Tools to Understand Immunogenic Breadth in the Context of a CD8 T-Cell Mediated HIV Response

Predictive models are becoming more and more commonplace as tools for candidate antigen discovery to meet the challenges of enabling epitope mapping of cohorts with diverse HLA properties. Here we build on the concept of using two key parameters, diversity metric of the HLA profile of individuals wi...

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Detalles Bibliográficos
Autores principales: McGowan, Ed, Rosenthal, Rachel, Fiore-Gartland, Andrew, Macharia, Gladys, Balinda, Sheila, Kapaata, Anne, Umviligihozo, Gisele, Muok, Erick, Dalel, Jama, Streatfield, Claire L., Coutinho, Helen, Dilernia, Dario, Monaco, Daniela C., Morrison, David, Yue, Ling, Hunter, Eric, Nielsen, Morten, Gilmour, Jill, Hare, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7930081/
https://www.ncbi.nlm.nih.gov/pubmed/33679745
http://dx.doi.org/10.3389/fimmu.2021.609884

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