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Epigenome-wide association study on asthma and chronic obstructive pulmonary disease overlap reveals aberrant DNA methylations related to clinical phenotypes

We hypothesized that epigenetics is a link between smoking/allergen exposures and the development of Asthma and chronic obstructive pulmonary disease (ACO). A total of 75 of 228 COPD patients were identified as ACO, which was independently associated with increased exacerbations. Microarray analysis...

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Detalles Bibliográficos
Autores principales: Chen, Yung-Che, Tsai, Ying-Huang, Wang, Chin-Chou, Liu, Shih-Feng, Chen, Ting-Wen, Fang, Wen-Feng, Lee, Chiu-Ping, Hsu, Po-Yuan, Chao, Tung-Ying, Wu, Chao-Chien, Wei, Yu-Feng, Chang, Huang-Chih, Tsen, Chia-Cheng, Chang, Yu-Ping, Lin, Meng-Chih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7930096/
https://www.ncbi.nlm.nih.gov/pubmed/33658578
http://dx.doi.org/10.1038/s41598-021-83185-1