Single-cell RNA sequencing reveals that targeting HSP90 suppresses PDAC progression by restraining mitochondrial bioenergetics

Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers, which lacks effective treatment strategies. There is an urgent need for the development of new strategies for PDAC therapy. The genetic and phenotypic heterogeneity of PDAC cancer cell populations poses further challenges in th...

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Detalles Bibliográficos
Autores principales: Hu, Li-Peng, Zhou, Kai-Xia, Huo, Yan-Miao, Liu, De-Jun, Li, Qing, Yang, Min-Wei, Huang, Pei-Qi, Xu, Chun-Jie, Tian, Guang-Ang, Yao, Lin-Li, Zhang, Xue-Li, Wang, Ya-Hui, Li, Jun, Zhang, Zhi-Gang, Jiang, Shu-Heng, Xing, Xin, Wang, Xu, Qin, Wei-Ting, Yang, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7930118/
https://www.ncbi.nlm.nih.gov/pubmed/33658487
http://dx.doi.org/10.1038/s41389-021-00311-4

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