Cargando…

T-cell CX3CR1 expression as a dynamic blood-based biomarker of response to immune checkpoint inhibitors

Immune checkpoint inhibitors (ICI) have revolutionized treatment for various cancers; however, durable response is limited to only a subset of patients. Discovery of blood-based biomarkers that reflect dynamic change of the tumor microenvironment, and predict response to ICI, will markedly improve c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yamauchi, Takayoshi, Hoki, Toshifumi, Oba, Takaaki, Jain, Vaibhav, Chen, Hongbin, Attwood, Kristopher, Battaglia, Sebastiano, George, Saby, Chatta, Gurkamal, Puzanov, Igor, Morrison, Carl, Odunsi, Kunle, Segal, Brahm H., Dy, Grace K., Ernstoff, Marc S., Ito, Fumito
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7930182/ https://www.ncbi.nlm.nih.gov/pubmed/33658501 http://dx.doi.org/10.1038/s41467-021-21619-0

Ejemplares similares

Predictive and Prognostic Implications of Circulating CX3CR1(+) CD8(+) T Cells in Non–Small Cell Lung Cancer Patients Treated with Chemo-Immunotherapy
por: Abdelfatah, Eihab, et al.
Publicado: (2023)

Fluctuations in Gut Microbiome Composition During Immune Checkpoint Inhibitor Therapy
por: Sarkar, Joy, et al.
Publicado: (2023)

Oncologist uptake of comprehensive genomic profile guided targeted therapy
por: Nesline, Mary K., et al.
Publicado: (2019)

Prostate cancer as a dedifferentiated organ: androgen receptor, cancer stem cells, and cancer stemness
por: Liu, Xiaozhuo, et al.
Publicado: (2022)

In situ delivery of iPSC-derived dendritic cells with local radiotherapy generates systemic antitumor immunity and potentiates PD-L1 blockade in preclinical poorly immunogenic tumor models
por: Oba, Takaaki, et al.
Publicado: (2021)

First-in-man application of a novel therapeutic cancer vaccine formulation with the capacity to induce multi-functional T cell responses in ovarian, breast and prostate cancer patients
por: Berinstein, Neil L, et al.
Publicado: (2012)

Role of tumor microenvironment in the efficacy of BCG therapy
por: Ibrahim, Omar M, et al.
Publicado: (2020)

Correction to: Tcf‑1 protects anti‑tumor TCR‑engineered CD8(+) T‑cells from GzmB mediated self‑destruction
por: Zangari, Brendan, et al.
Publicado: (2022)

Tcf-1 protects anti-tumor TCR-engineered CD8(+) T-cells from GzmB mediated self-destruction
por: Zangari, Brendan, et al.
Publicado: (2022)

Neoantigens retention in patient derived xenograft models mediates autologous T cells activation in ovarian cancer
por: Want, Muzamil Yaqub, et al.
Publicado: (2019)

Treatment recommendations to cancer patients in the context of FDA guidance for next generation sequencing
por: Dy, Grace K., et al.
Publicado: (2019)

Inhibition of EZH2 induces NK cell-mediated differentiation and death in muscle-invasive bladder cancer
por: Ramakrishnan, Swathi, et al.
Publicado: (2019)

Optimization of Radium-223 Treatment of Castration-resistant Prostate Cancer Based on the Burden of Skeletal Metastasis and Clinical Parameters
por: Shariftabrizi, Ahmad, et al.
Publicado: (2023)

NFκB-Activated COX2/PGE(2)/EP4 Axis Controls the Magnitude and Selectivity of BCG-Induced Inflammation in Human Bladder Cancer Tissues
por: Ibrahim, Omar M., et al.
Publicado: (2021)

Decitabine, a DNA-demethylating agent, promotes differentiation via NOTCH1 signaling and alters immune-related pathways in muscle-invasive bladder cancer
por: Ramakrishnan, Swathi, et al.
Publicado: (2017)

Enhanced efficacy of sitravatinib in metastatic models of antiangiogenic therapy resistance
por: Dolan, Melissa, et al.
Publicado: (2019)

Myeloid-Derived Suppressor Cells Modulate Immune Responses Independently of NADPH Oxidase in the Ovarian Tumor Microenvironment in Mice
por: Godoy, Heidi E., et al.
Publicado: (2013)

Cytomegalovirus reactivation after CD19 CAR T-cell therapy is clinically significant
por: Chen, George, et al.
Publicado: (2022)

Loss of MAGEC3 Expression Is Associated with Prognosis in Advanced Ovarian Cancers
por: Ellegate, James, et al.
Publicado: (2022)

The Interplay of Cx26, Cx32, Cx37, Cx40, Cx43, Cx45, and Panx1 in Inner-Ear Development of Yotari (dab1−/−) Mice and Humans
por: Lesko, Josip, et al.
Publicado: (2022)

The “Great Debate” at Immunotherapy Bridge 2022, Naples, November 30th–December 1st, 2022
por: Ascierto, Paolo A., et al.
Publicado: (2023)

Cardiac Toxicity Associated with Immune Checkpoint Inhibitors: Case Series and Review of the Literature
por: Agrawal, Nikhil, et al.
Publicado: (2019)

Correlations of Differentially Expressed Gap Junction Connexins Cx26, Cx30, Cx32, Cx43 and Cx46 with Breast Cancer Progression and Prognosis
por: Teleki, Ivett, et al.
Publicado: (2014)

Targeting myeloid cells in the tumor microenvironment enhances vaccine efficacy in murine epithelial ovarian cancer
por: Khan, Anm Nazmul H., et al.
Publicado: (2015)

Cost-Effectiveness Analysis of Adjuvant Stage III Colon Cancer Treatment at Veterans Affairs Medical Centers
por: Soni, Amy, et al.
Publicado: (2015)

NY-ESO-1 Cancer Testis Antigen Demonstrates High Immunogenicity in Triple Negative Breast Cancer
por: Ademuyiwa, Foluso O., et al.
Publicado: (2012)

Correction: NY-ESO-1 Cancer Testis Antigen Demonstrates High Immunogenicity in Triple Negative Breast Cancer
por: Ademuyiwa, Foluso O., et al.
Publicado: (2012)

Mutations of CX46/CX50 and Cataract Development
por: Shi, Yumeng, et al.
Publicado: (2022)

Chronic Stress and Gonadectomy Affect the Expression of Cx37, Cx40 and Cx43 in the Spinal Cord
por: Jurić, Marija, et al.
Publicado: (2021)

Local, multimodal intralesional therapy renders distant brain metastases susceptible to PD-L1 blockade in a preclinical model of triple-negative breast cancer
por: Yokoi, Toshihiro, et al.
Publicado: (2021)

COVID-19 and Cancer: a Comprehensive Review
por: Gosain, Rohit, et al.
Publicado: (2020)

Alteration of Cx37, Cx40, Cx43, Cx45, Panx1, and Renin Expression Patterns in Postnatal Kidneys of Dab1-/- (yotari) Mice
por: Lozić, Mirela, et al.
Publicado: (2021)

Diet-derived 25-hydroxyvitamin D3 activates vitamin D receptor target gene expression and suppresses EGFR mutant non-small cell lung cancer growth in vitro and in vivo
por: Verone-Boyle, Alissa R., et al.
Publicado: (2015)

Identification of Claudin 6-specific HLA class I- and HLA class II-restricted T cell receptors for cellular immunotherapy in ovarian cancer
por: Matsuzaki, Junko, et al.
Publicado: (2022)

Immuno-stimultory/regulatory gene expression patterns in advanced ovarian cancer
por: Eng, Kevin H., et al.
Publicado: (2015)

Augmenting antibody response to EGF-depleting immunotherapy: Findings from a phase I trial of CIMAvax-EGF in combination with nivolumab in advanced stage NSCLC
por: Evans, Rachel, et al.
Publicado: (2022)

A randomized phase II study of pazopanib in hormone sensitive prostate cancer: a University of Chicago Phase II Consortium/ Department of Defense Prostate Cancer Clinical Trials Consortium study
por: Ward, James E., et al.
Publicado: (2011)

Comparative Analysis of Cx31 and Cx43 in Differentiation-Competent Rodent Keratinocytes
por: Au, Akina, et al.
Publicado: (2020)

Editorial: Neutrophils in Cancer
por: Segal, Brahm H., et al.
Publicado: (2022)

Cardiac Cx43, Cx40 and Cx45 co-assembling: involvement of connexins epitopes in formation of hemichannels and Gap junction channels
por: Desplantez, Thomas
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_em3bbpktjt5hp2lm2sgh4bgof4