A critical period of neuronal activity results in aberrant neurogenesis rewiring hippocampal circuitry in a mouse model of epilepsy

In the mammalian hippocampus, adult-born granule cells (abGCs) contribute to the function of the dentate gyrus (DG). Disruption of the DG circuitry causes spontaneous recurrent seizures (SRS), which can lead to epilepsy. Although abGCs contribute to local inhibitory feedback circuitry, whether they...

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Detalles Bibliográficos
Autores principales: Lybrand, Zane R., Goswami, Sonal, Zhu, Jingfei, Jarzabek, Veronica, Merlock, Nikolas, Aktar, Mahafuza, Smith, Courtney, Zhang, Ling, Varma, Parul, Cho, Kyung-Ok, Ge, Shaoyu, Hsieh, Jenny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7930276/
https://www.ncbi.nlm.nih.gov/pubmed/33658509
http://dx.doi.org/10.1038/s41467-021-21649-8

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