Cargando…

The Human ApoE4 Variant Reduces Functional Recovery and Neuronal Sprouting After Incomplete Spinal Cord Injury in Male Mice

Spinal cord injury (SCI) is a devastating form of neurotrauma. Patients who carry one or two apolipoprotein E (ApoE)4 alleles show worse functional outcomes and longer hospital stays after SCI, but the cellular and molecular underpinnings for this genetic link remain poorly understood. Thus, there i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Toro, Carlos A., Hansen, Jens, Siddiq, Mustafa M., Johnson, Kaitlin, Zhao, Wei, Azulai, Daniella, Das, Dibash K., Bauman, William, Sebra, Robert, Cai, Dongming, Iyengar, Ravi, Cardozo, Christopher P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7930340/ https://www.ncbi.nlm.nih.gov/pubmed/33679326 http://dx.doi.org/10.3389/fncel.2021.626192

Ejemplares similares

Synaptojanin 1 Modulates Functional Recovery After Incomplete Spinal Cord Injury in Male Apolipoprotein E Epsilon 4 Mice
por: Toro, Carlos A., et al.
Publicado: (2023)

Boldine modulates glial transcription and functional recovery in a murine model of contusion spinal cord injury
por: Toro, Carlos A., et al.
Publicado: (2023)

Spinal cord injury regulates circular RNA expression in axons
por: Siddiq, Mustafa M., et al.
Publicado: (2023)

Spinal Cord Injury Reduces Serum Levels of Fibroblast Growth Factor-21 and Impairs Its Signaling Pathways in Liver and Adipose Tissue in Mice
por: Liu, Xin-Hua, et al.
Publicado: (2021)

Contusion spinal cord injury upregulates p53 protein expression in rat soleus muscle at multiple timepoints but not key senescence cytokines
por: Graham, Zachary A., et al.
Publicado: (2020)

Effects of a High-Fat Diet on Tissue Mass, Bone, and Glucose Tolerance after Chronic Complete Spinal Cord Transection in Male Mice
por: Graham, Zachary A., et al.
Publicado: (2020)

Extrinsic inhibitors in axon sprouting and functional recovery after spinal cord injury
por: Meves, Jessica M., et al.
Publicado: (2014)

Inosine Enhances Axon Sprouting and Motor Recovery after Spinal Cord Injury
por: Kim, Daniel, et al.
Publicado: (2013)

A spatially specified systems pharmacology therapy for axonal recovery after injury
por: Siddiq, Mustafa M., et al.
Publicado: (2023)

Contralateral Axon Sprouting but Not Ipsilateral Regeneration Is Responsible for Spontaneous Locomotor Recovery Post Spinal Cord Hemisection
por: Cao, Yudong, et al.
Publicado: (2021)

Comparison of gene expression profile of the spinal cord of sprouting-capable neonatal and sprouting-incapable adult mice
por: Tsujioka, Hiroshi, et al.
Publicado: (2019)

Dynamic balance between vesicle transport and microtubule growth enables neurite outgrowth
por: Yadaw, Arjun Singh, et al.
Publicado: (2019)

Extracellular histones, a new class of inhibitory molecules of CNS axonal regeneration
por: Siddiq, Mustafa M, et al.
Publicado: (2021)

Water Transfer Between Bamboo Culms in the Period of Sprouting
por: Fang, Dongming, et al.
Publicado: (2019)

Magnetic resonance imaging features of dogs with incomplete recovery after acute, severe spinal cord injury
por: Lewis, Melissa J., et al.
Publicado: (2017)

Effect of the Timing of Surgery on Neurological Recovery for Patients with Incomplete Paraplegia Caused by Metastatic Spinal Cord Compression
por: Cui, Yunpeng, et al.
Publicado: (2021)

Incomplete Recovery of Zebrafish Retina Following Cryoinjury
por: Džulová, Denisa, et al.
Publicado: (2022)

Novel Influences of Sex and APOE Genotype on Spinal Plasticity and Recovery of Function after Spinal Cord Injury
por: Strattan, Lydia E., et al.
Publicado: (2021)

Effect of Locomotor Training on Motor Recovery and Walking Ability in Patients with Incomplete Spinal Cord Injury: A Case Series
por: Anwer, Shahnawaz, et al.
Publicado: (2014)

Repairing the injured spinal cord: sprouting versus regeneration. Is this a realistic match?
por: Fouad, Karim, et al.
Publicado: (2014)

Grafted Human Embryonic Progenitors Expressing Neurogenin-2 Stimulate Axonal Sprouting and Improve Motor Recovery after Severe Spinal Cord Injury
por: Perrin, Florence E., et al.
Publicado: (2010)

Human Embryonic Stem Cell–derived Neural Crest Cells Promote Sprouting and Motor Recovery Following Spinal Cord Injury in Adult Rats
por: Jones, Iwan, et al.
Publicado: (2021)

Induction of central nervous system plasticity by repetitive transcranial magnetic stimulation to promote sensorimotor recovery in incomplete spinal cord injury
por: Ellaway, Peter H., et al.
Publicado: (2014)

GDF10 Is a Signal for Axonal Sprouting and Functional Recovery after Stroke
por: Li, S, et al.
Publicado: (2015)

Prevention of Preharvest Sprouting through Hormone Engineering and Germination Recovery by Chemical Biology
por: Nonogaki, Mariko, et al.
Publicado: (2017)

Retraining walking adaptability following incomplete spinal cord injury
por: Fox, Emily J., et al.
Publicado: (2017)

Breeding of Buckwheat for Usage of Sprout and Pre-Harvest Sprouting Resistance
por: Suzuki, Tatsuro, et al.
Publicado: (2021)

Neuronal sFlt1 and Vegfaa determine venous sprouting and spinal cord vascularization
por: Wild, Raphael, et al.
Publicado: (2017)

Incomplete and late recovery of sudden olfactory dysfunction in COVID-19()()
por: Kosugi, Eduardo Macoto, et al.
Publicado: (2020)

Partitioning of respired CO(2) in newly sprouted Moso bamboo culms
por: Ye, Chongyu, et al.
Publicado: (2023)

Dysbiosis and early mortality in zebrafish larvae exposed to subclinical concentrations of streptomycin
por: Pindling, Sydney, et al.
Publicado: (2018)

MicroRNA-4719 and microRNA-6756-5p Correlate with Castration-Resistant Prostate Cancer Progression through Interleukin-24 Regulation
por: Das, Dibash K., et al.
Publicado: (2019)

Sympathetic skin response in incomplete spinal cord injury with urinary incontinence
por: Emad, Reza, et al.
Publicado: (2013)

Reorganization of the somatosensory pathway after subacute incomplete cervical cord injury
por: Chen, Qian, et al.
Publicado: (2019)

Ankle proprioception during gait in individuals with incomplete spinal cord injury
por: Dambreville, Charline, et al.
Publicado: (2019)

Different hydraulic and photosynthetic responses to summer drought between newly sprouted and established Moso bamboo culms
por: Zhang, Xin, et al.
Publicado: (2023)

The Extracellular Environment of the CNS: Influence on Plasticity, Sprouting, and Axonal Regeneration after Spinal Cord Injury
por: Quraishe, Shmma, et al.
Publicado: (2018)

Treadmill step training promotes spinal cord neural plasticity after incomplete spinal cord injury
por: Sun, Tiansheng, et al.
Publicado: (2013)

Incomplete Spinal Cord Injury Reverses the Level-Dependence of Spinal Cord Injury Immune Deficiency Syndrome
por: Hong, James, et al.
Publicado: (2019)

Modelling Tumor-induced Angiogenesis: Combination of Stochastic Sprout Spacing and Sprout Progression
por: Hosseini, F., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_44235ij325cthpcf0o74hqt4i6