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Dynamic 3D Locus Organization and Its Drivers Underpin Immunoglobulin Recombination
A functional adaptive immune system must generate enormously diverse antigen receptor (AgR) repertoires from a limited number of AgR genes, using a common mechanism, V(D)J recombination. The AgR loci are among the largest in the genome, and individual genes must overcome huge spatial and temporal ch...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7930373/ https://www.ncbi.nlm.nih.gov/pubmed/33679727 http://dx.doi.org/10.3389/fimmu.2020.633705 |