SLC7A11 Reduces Laser-Induced Choroidal Neovascularization by Inhibiting RPE Ferroptosis and VEGF Production

In age-related macular degeneration (AMD), one of the principal sources of vascular endothelial growth factor (VEGF) is retinal pigment epithelium (RPE) cells under hypoxia or oxidative stress. Solute carrier family 7 member 11 (SLC7A11), a key component of cystine/glutamate transporter, regulates t...

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Detalles Bibliográficos
Autores principales: Zhao, Xiaohuan, Gao, Min, Liang, Jian, Chen, Yuhong, Wang, Yimin, Wang, Yuwei, Xiao, Yushu, Zhao, Zhenzhen, Wan, Xiaoling, Jiang, Mei, Luo, Xueting, Wang, Feng, Sun, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7930391/
https://www.ncbi.nlm.nih.gov/pubmed/33681224
http://dx.doi.org/10.3389/fcell.2021.639851

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7930391/
https://www.ncbi.nlm.nih.gov/pubmed/33681224
http://dx.doi.org/10.3389/fcell.2021.639851

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