Peripheral blood BRCA1 methylation profiling to predict familial ovarian cancer

OBJECTIVE: Familial cancer appears at a young age and its incidence is increasing. About 12% of familial ovarian cancer cases are associated with BRCA1/2 mutations (BRCAm). In this study, we investigated BRCA1 methylation may predict ovarian cancer in those with a family history of cancer (FHC) but...

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Detalles Bibliográficos
Autores principales: Jung, Yuyeon, Hur, Sooyoung, Liu, JingJing, Lee, Sanha, Kang, Byung Soo, Kim, Myungshin, Choi, Youn Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Asian Society of Gynecologic Oncology; Korean Society of Gynecologic Oncology; Japan Society of Gynecologic Oncology 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7930454/
https://www.ncbi.nlm.nih.gov/pubmed/33470065
http://dx.doi.org/10.3802/jgo.2021.32.e23

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