Interchangeability, immunogenicity and safety of a combined 10-valent pneumococcal Haemophilus influenzae protein D conjugate vaccine (Synflorix) and 13-valent-PCV (Prevenar13) schedule at 1-2-4-6 months: PREVIX_COMBO, a 3-arm randomised controlled trial

BACKGROUND: Aboriginal children living in remote communities are at high risk of early and persistent otitis media. Streptococcus pneumoniae and non-typeable Haemophilus influenzae (NTHi) are primary pathogens. Vaccines with potential to prevent early OM have not been evaluated in this population. W...

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Detalles Bibliográficos
Autores principales: Leach, Amanda Jane, Mulholland, Edward Kim, Santosham, Mathuram, Torzillo, Paul John, McIntyre, Peter, Smith-Vaughan, Heidi, Wilson, Nicole, Arrowsmith, Beth, Beissbarth, Jemima, Chatfield, Mark D., Oguoma, Victor M., Licciardi, Paul, Skull, Sue, Andrews, Ross, Carapetis, Jonathan, McDonnell, Joseph, Krause, Vicki, Morris, Peter Stanley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Regular paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7930582/
https://www.ncbi.nlm.nih.gov/pubmed/33681756
http://dx.doi.org/10.1016/j.jvacx.2021.100086

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