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Encapsulation of Andrographolide in poly(lactide-co-glycolide) Nanoparticles: Formulation Optimization and in vitro Efficacy Studies

Andrographolide is a potential chemopreventive and chemotherapeutic agent that suffers from poor aqueous solubility. Encapsulation in poly(lactide-co-glycolide) (PLGA) nanoparticles can overcome solubility issues and enable sustained release of the drug, resulting in improved therapeutic efficacy. I...

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Detalles Bibliográficos
Autores principales: Oseni, Bukola A., Azubuike, Chukwuemeka P., Okubanjo, Omotunde O., Igwilo, Cecilia I., Panyam, Jayanth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7930629/
https://www.ncbi.nlm.nih.gov/pubmed/33681172
http://dx.doi.org/10.3389/fbioe.2021.639409

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