Functional Expression of the Human Glucose Transporters GLUT2 and GLUT3 in Yeast Offers Novel Screening Systems for GLUT-Targeting Drugs

Human GLUT2 and GLUT3, members of the GLUT/SLC2 gene family, facilitate glucose transport in specific tissues. Their malfunction or misregulation is associated with serious diseases, including diabetes, metabolic syndrome, and cancer. Despite being promising drug targets, GLUTs have only a few speci...

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Detalles Bibliográficos
Autores principales: Schmidl, Sina, Tamayo Rojas, Sebastian A., Iancu, Cristina V., Choe, Jun-Yong, Oreb, Mislav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7930720/
https://www.ncbi.nlm.nih.gov/pubmed/33681287
http://dx.doi.org/10.3389/fmolb.2020.598419

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7930720/
https://www.ncbi.nlm.nih.gov/pubmed/33681287
http://dx.doi.org/10.3389/fmolb.2020.598419

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