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Successful bronchial arterial infusion chemotherapy combined with radiotherapy for an endobronchial metastasis after resection of small cell lung cancer

Bronchial arterial infusion (BAI) chemotherapy has been reported to be an effective treatment option for centrally located early‐stage squamous cell lung cancer (SCC) and has a favourable response rates for patients with stage III or IV or recurrent non‐small cell lung cancer (NSCLC) without distant...

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Detalles Bibliográficos
Autores principales: Horio, Yoshitsugu, Sato, Yozo, Tachibana, Hiroyuki, Hosoda, Waki, Shimizu, Junichi, Hida, Toyoaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7930754/
https://www.ncbi.nlm.nih.gov/pubmed/33728051
http://dx.doi.org/10.1002/rcr2.728
Descripción
Sumario:Bronchial arterial infusion (BAI) chemotherapy has been reported to be an effective treatment option for centrally located early‐stage squamous cell lung cancer (SCC) and has a favourable response rates for patients with stage III or IV or recurrent non‐small cell lung cancer (NSCLC) without distant metastases who cannot tolerate standard chemotherapy. Here, we report a case of an 83‐year‐old male with a solitary polypoid endobronchial metastatic tumour in the left main bronchus one year and 10 months after video‐assisted thoracoscopic surgery (VATS) combined segmentectomy (left S6 + S8a) for small cell lung cancer (SCLC), pT1bN0. He was treated with BAI of 100 mg of cis‐Diamminedichloroplatinum/cisplatin (CDDP), followed by thoracic radiotherapy (56 Gy in 28 fractions). There was no recurrence for 2.5 years. BAI chemotherapy combined with radiotherapy seemed to be an effective salvage option for the treatment of solitary endobronchial metastases of SCLC in patients unfit for standard chemoradiotherapy.