The Structural Understanding of Transthyretin Misfolding and the Inspired Drug Approaches for the Treatment of Heart Failure Associated With Transthyretin Amyloidosis

Substantial controversies exist in the exploration of the molecular mechanism of heart failure (HF) and pose challenges to the diagnosis of HF and the discovery of specific drugs for the treatment. Recently, cardiac transthyretin (TTR) amyloidosis is becoming recognized as one of major causes of und...

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Detalles Bibliográficos
Autores principales: He, Shan, He, Xinyue, Liu, Lei, Zhang, Wenbo, Yu, Lanlan, Deng, Zhun, Feiyi, Zhang, Mo, Shanshan, Fan, Yue, Zhao, Xinyue, Wang, Lun, Wang, Chenxuan, Zhang, Shuyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7930814/
https://www.ncbi.nlm.nih.gov/pubmed/33679409
http://dx.doi.org/10.3389/fphar.2021.628184

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