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Current Limitations and Candidate Potential of 5-HT7 Receptor Antagonism in Psychiatric Pharmacotherapy

Several mood-stabilizing atypical antipsychotics and antidepressants weakly block serotonin (5-HT) receptor type-7 (5-HT7R); however, the contributions of 5-HT7R antagonism to clinical efficacy and pathophysiology are yet to be clarified. A novel mood-stabilizing antipsychotic agent, lurasidone exhi...

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Detalles Bibliográficos
Autores principales: Okubo, Ruri, Hasegawa, Toshiki, Fukuyama, Kouji, Shiroyama, Takashi, Okada, Motohiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7930824/
https://www.ncbi.nlm.nih.gov/pubmed/33679481
http://dx.doi.org/10.3389/fpsyt.2021.623684