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Impact of Pharmacogenomic Information on Values of Care and Quality of Life Associated with Codeine and Tramadol-Related Adverse Drug Events
OBJECTIVE: To assess the potential impact of Pharmacogenomic (PGx) variation in cytochrome P450 2D6 (CYP2D6) enzyme function, using loss in quality-adjusted life years (QALYs) associated with treatment problems, and the willingness to pay to avoid treatment problems from patients’ and payers’ perspe...
Autores principales: | Zhu, Ye, Lopes, Guilherme S., Bielinski, Suzette J., Borah, Bijan J., Larson, Nicholas B., Moyer, Ann M., Olson, Janet E., Wang, Liewei, Weinshilboum, Richard, St. Sauver, Jennifer L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7930862/ https://www.ncbi.nlm.nih.gov/pubmed/33718782 http://dx.doi.org/10.1016/j.mayocpiqo.2020.08.009 |
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