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Presence of SARS-CoV-2 RNA in Semen—Cohort Study in the United States COVID-19 Positive Patients

On 31 December 2019, China informed the World Health Organization they were facing a viral pneumonia epidemic of a new type of Coronavirus. Currently, 10 months later, more than 43,000,000 people have been infected, and about 1,150,000 deceased worldwide from the disease. Knowledge about the virus i...

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Autores principales: Machado, Bruno, Barcelos Barra, Gustavo, Scherzer, Nickolas, Massey, Jack, dos Santos Luz, Hemerson, Henrique Jacomo, Rafael, Herinques Santa Rita, Ticiane, Davis, Rodney
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7930957/
https://www.ncbi.nlm.nih.gov/pubmed/33557147
http://dx.doi.org/10.3390/idr13010012
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author Machado, Bruno
Barcelos Barra, Gustavo
Scherzer, Nickolas
Massey, Jack
dos Santos Luz, Hemerson
Henrique Jacomo, Rafael
Herinques Santa Rita, Ticiane
Davis, Rodney
author_facet Machado, Bruno
Barcelos Barra, Gustavo
Scherzer, Nickolas
Massey, Jack
dos Santos Luz, Hemerson
Henrique Jacomo, Rafael
Herinques Santa Rita, Ticiane
Davis, Rodney
author_sort Machado, Bruno
collection PubMed
description On 31 December 2019, China informed the World Health Organization they were facing a viral pneumonia epidemic of a new type of Coronavirus. Currently, 10 months later, more than 43,000,000 people have been infected, and about 1,150,000 deceased worldwide from the disease. Knowledge about the virus is updated daily, and its RNA was isolated from several human secretions, e.g., throat, saliva, pulmonary alveolar washing, and feces. So far, only one publication found the presence of SARS-CoV-2 in semen. In this 5-month cross-sectional study, we recruited 15 patients diagnosed with a positive nasal swab for SARS-CoV-2 with no or mild symptoms in our institution. A semen sample after a shower was retrieved and tested for viral RNA in the semen. The samples were tested for the viral RNA with RT-PCR with two different genetic probes. The samples were re-tested 24 h after the first test to confirm the results. The SARS-Cov-2 viral RNA was present in 1/15 patients [6.66%] in our sample. Even in a small sample, the RNA from SARS-CoV-2 can be isolated from human semen. This information should alert the scientific community and public health officials about a possible new form of transmission of the disease and long-term clinical effects on the population.
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spelling pubmed-79309572021-03-05 Presence of SARS-CoV-2 RNA in Semen—Cohort Study in the United States COVID-19 Positive Patients Machado, Bruno Barcelos Barra, Gustavo Scherzer, Nickolas Massey, Jack dos Santos Luz, Hemerson Henrique Jacomo, Rafael Herinques Santa Rita, Ticiane Davis, Rodney Infect Dis Rep Brief Report On 31 December 2019, China informed the World Health Organization they were facing a viral pneumonia epidemic of a new type of Coronavirus. Currently, 10 months later, more than 43,000,000 people have been infected, and about 1,150,000 deceased worldwide from the disease. Knowledge about the virus is updated daily, and its RNA was isolated from several human secretions, e.g., throat, saliva, pulmonary alveolar washing, and feces. So far, only one publication found the presence of SARS-CoV-2 in semen. In this 5-month cross-sectional study, we recruited 15 patients diagnosed with a positive nasal swab for SARS-CoV-2 with no or mild symptoms in our institution. A semen sample after a shower was retrieved and tested for viral RNA in the semen. The samples were tested for the viral RNA with RT-PCR with two different genetic probes. The samples were re-tested 24 h after the first test to confirm the results. The SARS-Cov-2 viral RNA was present in 1/15 patients [6.66%] in our sample. Even in a small sample, the RNA from SARS-CoV-2 can be isolated from human semen. This information should alert the scientific community and public health officials about a possible new form of transmission of the disease and long-term clinical effects on the population. MDPI 2021-02-04 /pmc/articles/PMC7930957/ /pubmed/33557147 http://dx.doi.org/10.3390/idr13010012 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Brief Report
Machado, Bruno
Barcelos Barra, Gustavo
Scherzer, Nickolas
Massey, Jack
dos Santos Luz, Hemerson
Henrique Jacomo, Rafael
Herinques Santa Rita, Ticiane
Davis, Rodney
Presence of SARS-CoV-2 RNA in Semen—Cohort Study in the United States COVID-19 Positive Patients
title Presence of SARS-CoV-2 RNA in Semen—Cohort Study in the United States COVID-19 Positive Patients
title_full Presence of SARS-CoV-2 RNA in Semen—Cohort Study in the United States COVID-19 Positive Patients
title_fullStr Presence of SARS-CoV-2 RNA in Semen—Cohort Study in the United States COVID-19 Positive Patients
title_full_unstemmed Presence of SARS-CoV-2 RNA in Semen—Cohort Study in the United States COVID-19 Positive Patients
title_short Presence of SARS-CoV-2 RNA in Semen—Cohort Study in the United States COVID-19 Positive Patients
title_sort presence of sars-cov-2 rna in semen—cohort study in the united states covid-19 positive patients
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7930957/
https://www.ncbi.nlm.nih.gov/pubmed/33557147
http://dx.doi.org/10.3390/idr13010012
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