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Discovery of Substituted (2-Aminooxazol-4-yl)Isoxazole-3-carboxylic Acids as Inhibitors of Bacterial Serine Acetyltransferase in the Quest for Novel Potential Antibacterial Adjuvants
Many bacteria and actinomycetales use L-cysteine biosynthesis to increase their tolerance to antibacterial treatment and establish a long-lasting infection. In turn, this might lead to the onset of antimicrobial resistance that currently represents one of the most menacing threats to public health w...
Autores principales: | Magalhães, Joana, Franko, Nina, Raboni, Samanta, Annunziato, Giannamaria, Tammela, Päivi, Bruno, Agostino, Bettati, Stefano, Armao, Stefano, Spadini, Costanza, Cabassi, Clotilde Silvia, Mozzarelli, Andrea, Pieroni, Marco, Campanini, Barbara, Costantino, Gabriele |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7931047/ https://www.ncbi.nlm.nih.gov/pubmed/33672408 http://dx.doi.org/10.3390/ph14020174 |
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