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Pulmonary Hyalinizing Granuloma: A Rare Cause of a Benign Lung Mass

Pulmonary hyalinizing granuloma (PHG) is a rare, benign lung disease of unknown etiology. It usually manifests as solitary and sometimes as multiple pulmonary nodules. It may have irregular margins, cavitation, or calcifications mimicking metastasis or primary lung neoplasm. It should be considered...

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Autores principales: Rahi, Mandeep Singh, Gunasekaran, Kulothungan, Amoah, Kwesi, Chowdhury, Farheen, Kwon, Jeff
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7931080/
https://www.ncbi.nlm.nih.gov/pubmed/33572722
http://dx.doi.org/10.3390/clinpract11010007
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author Rahi, Mandeep Singh
Gunasekaran, Kulothungan
Amoah, Kwesi
Chowdhury, Farheen
Kwon, Jeff
author_facet Rahi, Mandeep Singh
Gunasekaran, Kulothungan
Amoah, Kwesi
Chowdhury, Farheen
Kwon, Jeff
author_sort Rahi, Mandeep Singh
collection PubMed
description Pulmonary hyalinizing granuloma (PHG) is a rare, benign lung disease of unknown etiology. It usually manifests as solitary and sometimes as multiple pulmonary nodules. It may have irregular margins, cavitation, or calcifications mimicking metastasis or primary lung neoplasm. It should be considered in the differential diagnosis of pulmonary nodules or masses. In this report, we present an unusual case of incidental slow-growing lung mass in a patient with 30 pack-year smoking history, construction-based occupation. The pleural-based calcified nodule in the left upper lobe gradually increased in size over ten years without any hilar or mediastinal lymphadenopathy. For an accurate diagnosis, PET-scan and histopathological analysis through wedge resection by video-assisted thoracoscopic surgery (VATS) were done. The biopsy findings were consistent with pulmonary hyalinizing granuloma, a rare benign cause of lung mass with an excellent long-term prognosis.
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spelling pubmed-79310802021-03-05 Pulmonary Hyalinizing Granuloma: A Rare Cause of a Benign Lung Mass Rahi, Mandeep Singh Gunasekaran, Kulothungan Amoah, Kwesi Chowdhury, Farheen Kwon, Jeff Clin Pract Case Report Pulmonary hyalinizing granuloma (PHG) is a rare, benign lung disease of unknown etiology. It usually manifests as solitary and sometimes as multiple pulmonary nodules. It may have irregular margins, cavitation, or calcifications mimicking metastasis or primary lung neoplasm. It should be considered in the differential diagnosis of pulmonary nodules or masses. In this report, we present an unusual case of incidental slow-growing lung mass in a patient with 30 pack-year smoking history, construction-based occupation. The pleural-based calcified nodule in the left upper lobe gradually increased in size over ten years without any hilar or mediastinal lymphadenopathy. For an accurate diagnosis, PET-scan and histopathological analysis through wedge resection by video-assisted thoracoscopic surgery (VATS) were done. The biopsy findings were consistent with pulmonary hyalinizing granuloma, a rare benign cause of lung mass with an excellent long-term prognosis. MDPI 2021-01-29 /pmc/articles/PMC7931080/ /pubmed/33572722 http://dx.doi.org/10.3390/clinpract11010007 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Rahi, Mandeep Singh
Gunasekaran, Kulothungan
Amoah, Kwesi
Chowdhury, Farheen
Kwon, Jeff
Pulmonary Hyalinizing Granuloma: A Rare Cause of a Benign Lung Mass
title Pulmonary Hyalinizing Granuloma: A Rare Cause of a Benign Lung Mass
title_full Pulmonary Hyalinizing Granuloma: A Rare Cause of a Benign Lung Mass
title_fullStr Pulmonary Hyalinizing Granuloma: A Rare Cause of a Benign Lung Mass
title_full_unstemmed Pulmonary Hyalinizing Granuloma: A Rare Cause of a Benign Lung Mass
title_short Pulmonary Hyalinizing Granuloma: A Rare Cause of a Benign Lung Mass
title_sort pulmonary hyalinizing granuloma: a rare cause of a benign lung mass
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7931080/
https://www.ncbi.nlm.nih.gov/pubmed/33572722
http://dx.doi.org/10.3390/clinpract11010007
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