Prevalence and Determinants of Medication Adherence among Patients with HIV/AIDS in Southern Vietnam

This study was conducted to determine the prevalence and determinants of medication adherence among patients with HIV/AIDS in southern Vietnam. Methods: A cross-sectional study was conducted in a hospital in southern Vietnam from June to December 2019 on patients who began antiretroviral therapy (AR...

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Autores principales: Nguyen, Phuong M., Thach, Anh N., Pham, Xuan D., Lam, Anh N., Nguyen, Thao N. P., Duong, Chu X., Nguyen, Lam V., Nguyen, Thao H., Pham, Suol T., Taxis, Katja, Nguyen, Thang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7931092/
https://www.ncbi.nlm.nih.gov/pubmed/33562451
http://dx.doi.org/10.3390/idr13010014
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author Nguyen, Phuong M.
Thach, Anh N.
Pham, Xuan D.
Lam, Anh N.
Nguyen, Thao N. P.
Duong, Chu X.
Nguyen, Lam V.
Nguyen, Thao H.
Pham, Suol T.
Taxis, Katja
Nguyen, Thang
author_facet Nguyen, Phuong M.
Thach, Anh N.
Pham, Xuan D.
Lam, Anh N.
Nguyen, Thao N. P.
Duong, Chu X.
Nguyen, Lam V.
Nguyen, Thao H.
Pham, Suol T.
Taxis, Katja
Nguyen, Thang
author_sort Nguyen, Phuong M.
collection PubMed
description This study was conducted to determine the prevalence and determinants of medication adherence among patients with HIV/AIDS in southern Vietnam. Methods: A cross-sectional study was conducted in a hospital in southern Vietnam from June to December 2019 on patients who began antiretroviral therapy (ART) for at least 6 months. Using a designed questionnaire, patients were considered adherent if they took correct medicines with right doses, on time and properly with food and beverage and had follow-up visits as scheduled. Multivariable logistic regression was used to identify determinants of adherence. Key findings: A total of 350 patients (from 861 medical records) were eligible for the study. The majority of patients were male (62.9%), and the dominant age group (≥35 years old) accounted for 53.7% of patients. Sexual intercourse was the primary route of transmission of HIV (95.1%). The proportions of participants who took the correct medicine and at a proper dose were 98.3% and 86.3%, respectively. In total, 94.9% of participants took medicine appropriately in combination with food and beverage, and 75.7% of participants were strictly adherent to ART. The factors marital status (odds ratio (OR) = 2.54; 95%CI = 1.51–4.28), being away from home (OR = 1.7; 95%CI = 1.03–2.78), substance abuse (OR = 2.7; 95%CI = 1.44–5.05), general knowledge about ART (OR = 2.75; 95%CI = 1.67–4.53), stopping medication after improvement (OR = 4.16; 95%CI = 2.29–7.56) and self-assessment of therapy adherence (OR = 9.83; 95%CI = 5.44–17.77) were significantly associated with patients’ adherence. Conclusions: Three-quarters of patients were adherent to ART. Researchers should consider these determinants of adherence in developing interventions in further studies.
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spelling pubmed-79310922021-03-05 Prevalence and Determinants of Medication Adherence among Patients with HIV/AIDS in Southern Vietnam Nguyen, Phuong M. Thach, Anh N. Pham, Xuan D. Lam, Anh N. Nguyen, Thao N. P. Duong, Chu X. Nguyen, Lam V. Nguyen, Thao H. Pham, Suol T. Taxis, Katja Nguyen, Thang Infect Dis Rep Article This study was conducted to determine the prevalence and determinants of medication adherence among patients with HIV/AIDS in southern Vietnam. Methods: A cross-sectional study was conducted in a hospital in southern Vietnam from June to December 2019 on patients who began antiretroviral therapy (ART) for at least 6 months. Using a designed questionnaire, patients were considered adherent if they took correct medicines with right doses, on time and properly with food and beverage and had follow-up visits as scheduled. Multivariable logistic regression was used to identify determinants of adherence. Key findings: A total of 350 patients (from 861 medical records) were eligible for the study. The majority of patients were male (62.9%), and the dominant age group (≥35 years old) accounted for 53.7% of patients. Sexual intercourse was the primary route of transmission of HIV (95.1%). The proportions of participants who took the correct medicine and at a proper dose were 98.3% and 86.3%, respectively. In total, 94.9% of participants took medicine appropriately in combination with food and beverage, and 75.7% of participants were strictly adherent to ART. The factors marital status (odds ratio (OR) = 2.54; 95%CI = 1.51–4.28), being away from home (OR = 1.7; 95%CI = 1.03–2.78), substance abuse (OR = 2.7; 95%CI = 1.44–5.05), general knowledge about ART (OR = 2.75; 95%CI = 1.67–4.53), stopping medication after improvement (OR = 4.16; 95%CI = 2.29–7.56) and self-assessment of therapy adherence (OR = 9.83; 95%CI = 5.44–17.77) were significantly associated with patients’ adherence. Conclusions: Three-quarters of patients were adherent to ART. Researchers should consider these determinants of adherence in developing interventions in further studies. MDPI 2021-02-05 /pmc/articles/PMC7931092/ /pubmed/33562451 http://dx.doi.org/10.3390/idr13010014 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Nguyen, Phuong M.
Thach, Anh N.
Pham, Xuan D.
Lam, Anh N.
Nguyen, Thao N. P.
Duong, Chu X.
Nguyen, Lam V.
Nguyen, Thao H.
Pham, Suol T.
Taxis, Katja
Nguyen, Thang
Prevalence and Determinants of Medication Adherence among Patients with HIV/AIDS in Southern Vietnam
title Prevalence and Determinants of Medication Adherence among Patients with HIV/AIDS in Southern Vietnam
title_full Prevalence and Determinants of Medication Adherence among Patients with HIV/AIDS in Southern Vietnam
title_fullStr Prevalence and Determinants of Medication Adherence among Patients with HIV/AIDS in Southern Vietnam
title_full_unstemmed Prevalence and Determinants of Medication Adherence among Patients with HIV/AIDS in Southern Vietnam
title_short Prevalence and Determinants of Medication Adherence among Patients with HIV/AIDS in Southern Vietnam
title_sort prevalence and determinants of medication adherence among patients with hiv/aids in southern vietnam
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7931092/
https://www.ncbi.nlm.nih.gov/pubmed/33562451
http://dx.doi.org/10.3390/idr13010014
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