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Identification of Three Small Molecules That Can Selectively Influence Cellular Manganese Levels in a Mouse Striatal Cell Model

Manganese (Mn) is a biologically essential metal, critical as a cofactor for numerous enzymes such a glutamine synthetase and kinases such as ataxia-telangiectasia mutated (ATM). Similar to other essential metals such as iron and zinc, proper levels of Mn need to be achieved while simultaneously bei...

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Detalles Bibliográficos
Autores principales: Horning, Kyle J., Tang, Xueqi, Thomas, Morgan G., Aschner, Michael, Bowman, Aaron B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7931103/
https://www.ncbi.nlm.nih.gov/pubmed/33671818
http://dx.doi.org/10.3390/molecules26041175