Synthesis and Cytotoxic Activity of Novel Metal Complexes Derived from Methyl-3-(4-chlorophenyl)-3-hydroxy-2,2-dimethylpropanoate as Potential CDK8 Kinase Inhibitors

[Image: see text] Several metal complexes of methyl-3-(4-chlorophenyl)-3-hydroxy-2,2-dimethylpropanoate derivatives were synthesized and tested for their anti-tumor activities. The ligands include 3-(4-chlorophenyl)-3-hydroxy-2,2-dimethylpropanoic acid (1), 3-(4-chlorophenyl)-3-hydroxy-2,2-dimethylp...

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Detalles Bibliográficos
Autores principales: Aboelmagd, Ahmed, El Rayes, Samir M., Gomaa, Mohamed S., Fathalla, Walid, Ali, Ibrahim A. I., Nafie, Mohamed S., Pottoo, Faheem H., Khan, Firdos Alam, Ibrahim, Mohamed M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7931189/
https://www.ncbi.nlm.nih.gov/pubmed/33681565
http://dx.doi.org/10.1021/acsomega.0c05263

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7931189/
https://www.ncbi.nlm.nih.gov/pubmed/33681565
http://dx.doi.org/10.1021/acsomega.0c05263

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