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Hypermethylation of the PZP gene is associated with hepatocellular carcinoma cell proliferation, invasion and migration

Pregnancy zone protein (PZP), a member of the proteinase inhibitor I39 (‐2‐macroglobulin) family of proteins, is involved in the initiation and development of various tumors. The gene encoding PZP is hypermethylated and expressed at low levels in hepatocellular carcinoma (HCC) tissue and cells, but...

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Detalles Bibliográficos
Autores principales: Wu, Minhua, Lan, Hui, Ye, Zhongwei, Wang, Yonghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7931217/
https://www.ncbi.nlm.nih.gov/pubmed/33471436
http://dx.doi.org/10.1002/2211-5463.13093