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Structural snapshots of the kinesin‐2 OSM‐3 along its nucleotide cycle: implications for the ATP hydrolysis mechanism
Motile kinesins are motor proteins that translocate along microtubules as they hydrolyze ATP. They share a conserved motor domain which harbors both ATPase and microtubule‐binding activities. An ATP hydrolysis mechanism involving two water molecules has been proposed based on the structure of the ki...
Autores principales: | Varela, Paloma F., Chenon, Mélanie, Velours, Christophe, Verhey, Kristen J., Ménétrey, Julie, Gigant, Benoît |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7931232/ https://www.ncbi.nlm.nih.gov/pubmed/33513284 http://dx.doi.org/10.1002/2211-5463.13101 |
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