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Altered network properties in C9ORF72 repeat expansion cortical neurons are due to synaptic dysfunction

BACKGROUND: Physiological disturbances in cortical network excitability and plasticity are established and widespread in amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) patients, including those harbouring the C9ORF72 repeat expansion (C9ORF72(RE)) mutation – the most common ge...

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Detalles Bibliográficos
Autores principales:	Perkins, Emma M., Burr, Karen, Banerjee, Poulomi, Mehta, Arpan R., Dando, Owen, Selvaraj, Bhuvaneish T., Suminaite, Daumante, Nanda, Jyoti, Henstridge, Christopher M., Gillingwater, Thomas H., Hardingham, Giles E., Wyllie, David J. A., Chandran, Siddharthan, Livesey, Matthew R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7931347/ https://www.ncbi.nlm.nih.gov/pubmed/33663561 http://dx.doi.org/10.1186/s13024-021-00433-8

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