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GRK2 regulates GLP-1R-mediated early phase insulin secretion in vivo

BACKGROUND: Insulin secretion from the pancreatic β-cell is finely modulated by different signals to allow an adequate control of glucose homeostasis. Incretin hormones such as glucagon-like peptide-1 (GLP-1) act as key physiological potentiators of insulin release through binding to the G protein-c...

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Detalles Bibliográficos
Autores principales:	Arcones, Alba C., Vila-Bedmar, Rocío, Mirasierra, Mercedes, Cruces-Sande, Marta, Vallejo, Mario, Jones, Ben, Tomas, Alejandra, Mayor, Federico, Murga, Cristina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7931601/ https://www.ncbi.nlm.nih.gov/pubmed/33658023 http://dx.doi.org/10.1186/s12915-021-00966-w

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