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A mouse model of Huntington’s disease shows altered ultrastructure of transverse tubules in skeletal muscle fibers
Huntington’s disease (HD) is a fatal and progressive condition with severe debilitating motor defects and muscle weakness. Although classically recognized as a neurodegenerative disorder, there is increasing evidence of cell autonomous toxicity in skeletal muscle. We recently demonstrated that skele...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7931643/ https://www.ncbi.nlm.nih.gov/pubmed/33683318 http://dx.doi.org/10.1085/jgp.202012637 |