A mouse model of Huntington’s disease shows altered ultrastructure of transverse tubules in skeletal muscle fibers

Huntington’s disease (HD) is a fatal and progressive condition with severe debilitating motor defects and muscle weakness. Although classically recognized as a neurodegenerative disorder, there is increasing evidence of cell autonomous toxicity in skeletal muscle. We recently demonstrated that skele...

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Detalles Bibliográficos
Autores principales: Romer, Shannon H., Metzger, Sabrina, Peraza, Kristiana, Wright, Matthew C., Jobe, D. Scott, Song, Long-Sheng, Rich, Mark M., Foy, Brent D., Talmadge, Robert J., Voss, Andrew A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7931643/
https://www.ncbi.nlm.nih.gov/pubmed/33683318
http://dx.doi.org/10.1085/jgp.202012637

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