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Metformin Resensitizes Sorafenib-Resistant HCC Cells Through AMPK-Dependent Autophagy Activation
Despite the activation of autophagy may enable residual cancer cells to survive and allow tumor relapse, excessive activation of autophagy may eventually lead to cell death. However, the details of the association of autophagy with primary resistance in hepatocellular carcinoma (HCC) remain less cle...
Autores principales: | Lai, Hong-Yue, Tsai, Hsin-Hwa, Yen, Chia-Jui, Hung, Liang-Yi, Yang, Ching-Chieh, Ho, Chung-Han, Liang, Hsin-Yin, Chen, Feng-Wei, Li, Chien-Feng, Wang, Ju-Ming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7931828/ https://www.ncbi.nlm.nih.gov/pubmed/33681180 http://dx.doi.org/10.3389/fcell.2020.596655 |
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