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Assessment of Drug-Induced Toxicity Biomarkers in the Brain Microphysiological System (MPS) Using Targeted and Untargeted Molecular Profiling
Early assessment of adverse drug effects in humans is critical to avoid long-lasting harm. However, current approaches for early detection of adverse effects still lack predictive and organ-specific biomarkers to evaluate undesired responses in humans. Microphysiological systems (MPSs) are in vitro...
Autores principales: | Mina, Sara G., Alaybeyoglu, Begum, Murphy, William L., Thomson, James A., Stokes, Cynthia L., Cirit, Murat |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7931859/ https://www.ncbi.nlm.nih.gov/pubmed/33693346 http://dx.doi.org/10.3389/fdata.2019.00023 |
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