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Flow Assisted Mutation Enrichment (FAME): A highly efficacious and efficient method to enrich Double Knockouts (DKO) after gene editing

Gene editing has become an essential tool for interrogation of gene function in biomedical research and is also a promising approach for gene therapy. Despite recent progresses, the gene-editing procedure is still a tedious process involving manually isolating large number of single cell colonies to...

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Detalles Bibliográficos
Autores principales: Hansen, Michael, Cai, Xiaopin, Bowen, Sara, Largaespada, David A., Li, Ming V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7932066/
https://www.ncbi.nlm.nih.gov/pubmed/33661977
http://dx.doi.org/10.1371/journal.pone.0247375

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