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Characterization and trypanocidal activity of a β-lapachone-containing drug carrier
The treatment of Chagas disease (CD), a neglected parasitic condition caused by Trypanosoma cruzi, is still based on only two drugs, nifurtimox (Nif) and benznidazole (Bz), both of which have limited efficacy in the late chronic phase and induce severe side effects. This scenario justifies the conti...
Autores principales: | Barbosa, Juliana M. C., Nicoletti, Caroline D., da Silva, Patrícia B., Melo, Tatiana G., Futuro, Débora O., Ferreira, Vitor F., Salomão, Kelly |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7932091/ https://www.ncbi.nlm.nih.gov/pubmed/33661933 http://dx.doi.org/10.1371/journal.pone.0246811 |
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