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Study on mechanical properties and permeability of elliptical porous scaffold based on the SLM manufactured medical Ti6Al4V

In this paper, we take the elliptical pore structure which is similar to the microstructure of cancellous bone as the research object, four groups of bone scaffolds were designed from the perspective of pore size, porosity and pore distribution. The size of the all scaffolds were uniformly designed...

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Autores principales: Shi, Chenglong, Lu, Nana, Qin, Yaru, Liu, Mingdi, Li, Hongxia, Li, Haichao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7932120/
https://www.ncbi.nlm.nih.gov/pubmed/33661944
http://dx.doi.org/10.1371/journal.pone.0247764
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author Shi, Chenglong
Lu, Nana
Qin, Yaru
Liu, Mingdi
Li, Hongxia
Li, Haichao
author_facet Shi, Chenglong
Lu, Nana
Qin, Yaru
Liu, Mingdi
Li, Hongxia
Li, Haichao
author_sort Shi, Chenglong
collection PubMed
description In this paper, we take the elliptical pore structure which is similar to the microstructure of cancellous bone as the research object, four groups of bone scaffolds were designed from the perspective of pore size, porosity and pore distribution. The size of the all scaffolds were uniformly designed as 10 × 10 × 12 mm. Four groups of model samples were prepared by selective laser melting (SLM) and Ti6Al4V materials. The statics performance of the scaffolds was comprehensively evaluated by mechanical compression simulation and mechanical compression test, the manufacturing error of the scaffold samples were evaluated by scanning electron microscope (SEM), and the permeability of the scaffolds were predicted and evaluated by simulation analysis of computational fluid dynamics (CFD). The results show that the different distribution of porosity, pore size and pores of the elliptical scaffold have a certain influence on the mechanical properties and permeability of the scaffold, and the reasonable size and angle distribution of the elliptical pore can match the mechanical properties and permeability of the elliptical pore scaffold with human cancellous bone, which has great potential for research and application in the field of artificial bone scaffold.
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spelling pubmed-79321202021-03-10 Study on mechanical properties and permeability of elliptical porous scaffold based on the SLM manufactured medical Ti6Al4V Shi, Chenglong Lu, Nana Qin, Yaru Liu, Mingdi Li, Hongxia Li, Haichao PLoS One Research Article In this paper, we take the elliptical pore structure which is similar to the microstructure of cancellous bone as the research object, four groups of bone scaffolds were designed from the perspective of pore size, porosity and pore distribution. The size of the all scaffolds were uniformly designed as 10 × 10 × 12 mm. Four groups of model samples were prepared by selective laser melting (SLM) and Ti6Al4V materials. The statics performance of the scaffolds was comprehensively evaluated by mechanical compression simulation and mechanical compression test, the manufacturing error of the scaffold samples were evaluated by scanning electron microscope (SEM), and the permeability of the scaffolds were predicted and evaluated by simulation analysis of computational fluid dynamics (CFD). The results show that the different distribution of porosity, pore size and pores of the elliptical scaffold have a certain influence on the mechanical properties and permeability of the scaffold, and the reasonable size and angle distribution of the elliptical pore can match the mechanical properties and permeability of the elliptical pore scaffold with human cancellous bone, which has great potential for research and application in the field of artificial bone scaffold. Public Library of Science 2021-03-04 /pmc/articles/PMC7932120/ /pubmed/33661944 http://dx.doi.org/10.1371/journal.pone.0247764 Text en © 2021 Shi et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Shi, Chenglong
Lu, Nana
Qin, Yaru
Liu, Mingdi
Li, Hongxia
Li, Haichao
Study on mechanical properties and permeability of elliptical porous scaffold based on the SLM manufactured medical Ti6Al4V
title Study on mechanical properties and permeability of elliptical porous scaffold based on the SLM manufactured medical Ti6Al4V
title_full Study on mechanical properties and permeability of elliptical porous scaffold based on the SLM manufactured medical Ti6Al4V
title_fullStr Study on mechanical properties and permeability of elliptical porous scaffold based on the SLM manufactured medical Ti6Al4V
title_full_unstemmed Study on mechanical properties and permeability of elliptical porous scaffold based on the SLM manufactured medical Ti6Al4V
title_short Study on mechanical properties and permeability of elliptical porous scaffold based on the SLM manufactured medical Ti6Al4V
title_sort study on mechanical properties and permeability of elliptical porous scaffold based on the slm manufactured medical ti6al4v
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7932120/
https://www.ncbi.nlm.nih.gov/pubmed/33661944
http://dx.doi.org/10.1371/journal.pone.0247764
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