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Study on mechanical properties and permeability of elliptical porous scaffold based on the SLM manufactured medical Ti6Al4V
In this paper, we take the elliptical pore structure which is similar to the microstructure of cancellous bone as the research object, four groups of bone scaffolds were designed from the perspective of pore size, porosity and pore distribution. The size of the all scaffolds were uniformly designed...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7932120/ https://www.ncbi.nlm.nih.gov/pubmed/33661944 http://dx.doi.org/10.1371/journal.pone.0247764 |
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author | Shi, Chenglong Lu, Nana Qin, Yaru Liu, Mingdi Li, Hongxia Li, Haichao |
author_facet | Shi, Chenglong Lu, Nana Qin, Yaru Liu, Mingdi Li, Hongxia Li, Haichao |
author_sort | Shi, Chenglong |
collection | PubMed |
description | In this paper, we take the elliptical pore structure which is similar to the microstructure of cancellous bone as the research object, four groups of bone scaffolds were designed from the perspective of pore size, porosity and pore distribution. The size of the all scaffolds were uniformly designed as 10 × 10 × 12 mm. Four groups of model samples were prepared by selective laser melting (SLM) and Ti6Al4V materials. The statics performance of the scaffolds was comprehensively evaluated by mechanical compression simulation and mechanical compression test, the manufacturing error of the scaffold samples were evaluated by scanning electron microscope (SEM), and the permeability of the scaffolds were predicted and evaluated by simulation analysis of computational fluid dynamics (CFD). The results show that the different distribution of porosity, pore size and pores of the elliptical scaffold have a certain influence on the mechanical properties and permeability of the scaffold, and the reasonable size and angle distribution of the elliptical pore can match the mechanical properties and permeability of the elliptical pore scaffold with human cancellous bone, which has great potential for research and application in the field of artificial bone scaffold. |
format | Online Article Text |
id | pubmed-7932120 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-79321202021-03-10 Study on mechanical properties and permeability of elliptical porous scaffold based on the SLM manufactured medical Ti6Al4V Shi, Chenglong Lu, Nana Qin, Yaru Liu, Mingdi Li, Hongxia Li, Haichao PLoS One Research Article In this paper, we take the elliptical pore structure which is similar to the microstructure of cancellous bone as the research object, four groups of bone scaffolds were designed from the perspective of pore size, porosity and pore distribution. The size of the all scaffolds were uniformly designed as 10 × 10 × 12 mm. Four groups of model samples were prepared by selective laser melting (SLM) and Ti6Al4V materials. The statics performance of the scaffolds was comprehensively evaluated by mechanical compression simulation and mechanical compression test, the manufacturing error of the scaffold samples were evaluated by scanning electron microscope (SEM), and the permeability of the scaffolds were predicted and evaluated by simulation analysis of computational fluid dynamics (CFD). The results show that the different distribution of porosity, pore size and pores of the elliptical scaffold have a certain influence on the mechanical properties and permeability of the scaffold, and the reasonable size and angle distribution of the elliptical pore can match the mechanical properties and permeability of the elliptical pore scaffold with human cancellous bone, which has great potential for research and application in the field of artificial bone scaffold. Public Library of Science 2021-03-04 /pmc/articles/PMC7932120/ /pubmed/33661944 http://dx.doi.org/10.1371/journal.pone.0247764 Text en © 2021 Shi et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Shi, Chenglong Lu, Nana Qin, Yaru Liu, Mingdi Li, Hongxia Li, Haichao Study on mechanical properties and permeability of elliptical porous scaffold based on the SLM manufactured medical Ti6Al4V |
title | Study on mechanical properties and permeability of elliptical porous scaffold based on the SLM manufactured medical Ti6Al4V |
title_full | Study on mechanical properties and permeability of elliptical porous scaffold based on the SLM manufactured medical Ti6Al4V |
title_fullStr | Study on mechanical properties and permeability of elliptical porous scaffold based on the SLM manufactured medical Ti6Al4V |
title_full_unstemmed | Study on mechanical properties and permeability of elliptical porous scaffold based on the SLM manufactured medical Ti6Al4V |
title_short | Study on mechanical properties and permeability of elliptical porous scaffold based on the SLM manufactured medical Ti6Al4V |
title_sort | study on mechanical properties and permeability of elliptical porous scaffold based on the slm manufactured medical ti6al4v |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7932120/ https://www.ncbi.nlm.nih.gov/pubmed/33661944 http://dx.doi.org/10.1371/journal.pone.0247764 |
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