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Rapid 3D phenotypic analysis of neurons and organoids using data-driven cell segmentation-free machine learning

Phenotypic profiling of large three-dimensional microscopy data sets has not been widely adopted due to the challenges posed by cell segmentation and feature selection. The computational demands of automated processing further limit analysis of hard-to-segment images such as of neurons and organoids...

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Detalles Bibliográficos
Autores principales: Mergenthaler, Philipp, Hariharan, Santosh, Pemberton, James M., Lourenco, Corey, Penn, Linda Z., Andrews, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7932518/
https://www.ncbi.nlm.nih.gov/pubmed/33617523
http://dx.doi.org/10.1371/journal.pcbi.1008630