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Developmental hourglass and heterochronic shifts in fin and limb development
How genetic changes are linked to morphological novelties and developmental constraints remains elusive. Here, we investigate genetic apparatuses that distinguish fish fins from tetrapod limbs by analyzing transcriptomes and open-chromatin regions (OCRs). Specifically, we compared mouse forelimb bud...
Autores principales: | Onimaru, Koh, Tatsumi, Kaori, Tanegashima, Chiharu, Kadota, Mitsutaka, Nishimura, Osamu, Kuraku, Shigehiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7932699/ https://www.ncbi.nlm.nih.gov/pubmed/33560225 http://dx.doi.org/10.7554/eLife.62865 |
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