A novel hypoxic long noncoding RNA KB-1980E6.3 maintains breast cancer stem cell stemness via interacting with IGF2BP1 to facilitate c-Myc mRNA stability

The hostile hypoxic microenvironment takes primary responsibility for the rapid expansion of breast cancer tumors. However, the underlying mechanism is not fully understood. Here, using RNA sequencing (RNA-seq) analysis, we identified a hypoxia-induced long noncoding RNA (lncRNA) KB-1980E6.3, which...

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Detalles Bibliográficos
Autores principales: Zhu, Pengpeng, He, Fang, Hou, Yixuan, Tu, Gang, Li, Qiao, Jin, Ting, Zeng, Huan, Qin, Yilu, Wan, Xueying, Qiao, Yina, Qiu, Yuxiang, Teng, Yong, Liu, Manran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7932928/
https://www.ncbi.nlm.nih.gov/pubmed/33469161
http://dx.doi.org/10.1038/s41388-020-01638-9

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