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Using the Microwell-mesh to culture microtissues in vitro and as a carrier to implant microtissues in vivo into mice
Prostate cancer (PCa) patient-derived xenografts (PDXs) are commonly propagated by serial transplantation of “pieces” of tumour in mice, but the cellular composition of pieces is not standardised. Herein, we optimised a microwell platform, the Microwell-mesh, to aggregate precise numbers of cells in...
Autores principales: | Monterosso, Melissa E., Futrega, Kathryn, Lott, William B., Vela, Ian, Williams, Elizabeth D., Doran, Michael R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933425/ https://www.ncbi.nlm.nih.gov/pubmed/33664329 http://dx.doi.org/10.1038/s41598-021-84154-4 |
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