Cargando…
Novel Bispecific Antibody for Synovial-Specific Target Delivery of Anti-TNF Therapy in Rheumatoid Arthritis
Biologic drugs, especially anti-TNF, are considered as the gold standard therapy in rheumatoid arthritis. However, non-uniform efficacy, incidence of infections, and high costs are major concerns. Novel tissue-specific agents may overcome the current limitations of systemic administration, providing...
Autores principales: | Ferrari, Mathieu, Onuoha, Shimobi C., Fossati-Jimack, Liliane, Nerviani, Alessandra, Alves, Pedro L., Pagani, Sara, Deantonio, Cecilia, Colombo, Federico, Santoro, Claudio, Sblattero, Daniele, Pitzalis, Costantino |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933454/ https://www.ncbi.nlm.nih.gov/pubmed/33679801 http://dx.doi.org/10.3389/fimmu.2021.640070 |
Ejemplares similares
-
Rational Design of Antirheumatic Prodrugs Specific for Sites of Inflammation
por: Onuoha, Shimobi C., et al.
Publicado: (2015) -
Follicular dendritic cell differentiation is associated with distinct synovial pathotype signatures in rheumatoid arthritis
por: El Shikh, Mohey Eldin M., et al.
Publicado: (2022) -
A Pauci-Immune Synovial Pathotype Predicts Inadequate Response to TNFα-Blockade in Rheumatoid Arthritis Patients
por: Nerviani, Alessandra, et al.
Publicado: (2020) -
Rituximab versus tocilizumab in rheumatoid arthritis: synovial biopsy-based biomarker analysis of the phase 4 R4RA randomized trial
por: Rivellese, Felice, et al.
Publicado: (2022) -
New Insights into the Role of Tyro3, Axl, and Mer Receptors in Rheumatoid Arthritis
por: Pagani, Sara, et al.
Publicado: (2020)