Cargando…

Vacuolar Membrane ATPase Activity 21 Predicts a Favorable Outcome and Acts as a Suppressor in Colorectal Cancer

Extracellular and/or intracellular manipulation of pH in tumor may have noticeable potential in cancer treatment. Although the assembly factor genes of V(0) domain of the V-ATPase complex are required for intracellular pH homeostasis, their significance in colorectal cancer (CRC) remains largely unk...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Fan, Shen, Hao, Fu, Yating, Yu, Guanyu, Cao, Fuao, Chang, Wenjun, Xie, Zhongdong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933500/ https://www.ncbi.nlm.nih.gov/pubmed/33680927 http://dx.doi.org/10.3389/fonc.2020.605801

Ejemplares similares

Eyes absent homologue 2 predicts a favorable prognosis in colorectal cancer
por: Zheng, Jie, et al.
Publicado: (2018)

Significance of the E3 ubiquitin protein UBR5 as an oncogene and a prognostic biomarker in colorectal cancer
por: Xie, Zhongdong, et al.
Publicado: (2017)

Role of the vacuolar ATPase in the Alphavirus replication cycle
por: Schuchman, Ryan M., et al.
Publicado: (2018)

Overexpression of the ATPase Inhibitory Factor 1 Favors a Non-metastatic Phenotype in Breast Cancer
por: García-Ledo, Lucía, et al.
Publicado: (2017)

Flexibility within the Rotor and Stators of the Vacuolar H(+)-ATPase
por: Song, Chun Feng, et al.
Publicado: (2013)

Rotating with the brakes on and other unresolved features of the vacuolar ATPase
por: Rawson, Shaun, et al.
Publicado: (2016)

The curious case of vacuolar ATPase: regulation of signaling pathways
por: Pamarthy, Sahithi, et al.
Publicado: (2018)

Advances in targeting the vacuolar proton-translocating ATPase (V-ATPase) for anti-fungal therapy
por: Hayek, Summer R., et al.
Publicado: (2014)

Nkx2.5 Functions as a Conditional Tumor Suppressor Gene in Colorectal Cancer Cells via Acting as a Transcriptional Coactivator in p53-Mediated p21 Expression
por: Li, Huili, et al.
Publicado: (2021)

An isoform of the vacuolar (H(+))-ATPase accessory subunit Ac45
por: Jansen, Eric J. R., et al.
Publicado: (2009)

The vacuolar H+ ATPase is a novel therapeutic target for glioblastoma
por: Di Cristofori, Andrea, et al.
Publicado: (2015)

Cryo-EM studies of the structure and dynamics of vacuolar-type ATPases
por: Mazhab-Jafari, Mohammad T., et al.
Publicado: (2016)

Vacuolar-type ATPase: A proton pump to lysosomal trafficking
por: FUTAI, Masamitsu, et al.
Publicado: (2019)

RNA Interference of Genes Encoding the Vacuolar-ATPase in Liriomyza trifolii
por: Chang, Ya-Wen, et al.
Publicado: (2021)

The vacuolar-ATPase (V-ATPase) modulates matrix metalloproteinase (MMP) isoforms in human pancreatic cancer
por: Chung, Chuhan, et al.
Publicado: (2011)

Involvement of MoVMA11, a Putative Vacuolar ATPase c’ Subunit, in Vacuolar Acidification and Infection-Related Morphogenesis of Magnaporthe oryzae
por: Chen, Guoqing, et al.
Publicado: (2013)

Cloning, Expression and Purification of Subunit H of Vacuolar H(+)-ATPase from Mythimna separata Walker (Lepidoptera: Noctuidae)
por: Lu, Lina, et al.
Publicado: (2014)

Acidification of the lysosome-like vacuole and the vacuolar H+-ATPase are deficient in two yeast mutants that fail to sort vacuolar proteins
Publicado: (1989)

Probing Subunit-Subunit Interactions in the Yeast Vacuolar ATPase by Peptide Arrays
por: Parsons, Lee S., et al.
Publicado: (2012)

Identification of Novel Bisbenzimidazole Derivatives as Anticancer Vacuolar (H(+))-ATPase Inhibitors †
por: Patil, Renukadevi, et al.
Publicado: (2017)

Vacuolar H(+)-ATPase is not restricted to clear cells of the epididymal epithelium in cattle
por: Kim, Sung Woo, et al.
Publicado: (2021)

The role of Plasmodium V-ATPase in vacuolar physiology and antimalarial drug uptake
por: Alder, Arne, et al.
Publicado: (2023)

Extracellular and Luminal pH Regulation by Vacuolar H(+)-ATPase Isoform Expression and Targeting to the Plasma Membrane and Endosomes
por: Smith, Gina A., et al.
Publicado: (2016)

High expression of phosphorylated focal adhesion kinase predicts a poor prognosis in human colorectal cancer
por: Yu, Guanyu, et al.
Publicado: (2022)

MicroRNA-142-3p Inhibits Tumorigenesis of Colorectal Cancer via Suppressing the Activation of Wnt Signaling by Directly Targeting to β-Catenin
por: Liu, Peng, et al.
Publicado: (2021)

Reconstitution of Vacuolar-type Rotary H(+)-ATPase/Synthase from Thermus thermophilus
por: Kishikawa, Jun-ichi, et al.
Publicado: (2012)

The Vacuolar-Type H(+)-ATPase in Ovine Rumen Epithelium is Regulated by Metabolic Signals
por: Kuzinski, Judith, et al.
Publicado: (2010)

Inhibition of Host Vacuolar H(+)-ATPase Activity by a Legionella pneumophila Effector
por: Xu, Li, et al.
Publicado: (2010)

The d subunit plays a central role in human vacuolar H(+)-ATPases
por: Smith, Annabel N., et al.
Publicado: (2008)

Retrieval of the Vacuolar H(+)-ATPase from Phagosomes Revealed by Live Cell Imaging
por: Clarke, Margaret, et al.
Publicado: (2010)

A thermo-physical analysis of the proton pump vacuolar-ATPase: the constructal approach
por: Lucia, Umberto, et al.
Publicado: (2014)

Structure of the Vacuolar H(+)-ATPase Rotary Motor Reveals New Mechanistic Insights
por: Rawson, Shaun, et al.
Publicado: (2015)

Vacuolar ATPase as a potential therapeutic target and mediator of treatment resistance in cancer
por: Whitton, Bradleigh, et al.
Publicado: (2018)

Clathrin coat controls synaptic vesicle acidification by blocking vacuolar ATPase activity
por: Farsi, Zohreh, et al.
Publicado: (2018)

Antiviral efficacy of nanoparticulate vacuolar ATPase inhibitors against influenza virus infection
por: Hu, Che-Ming Jack, et al.
Publicado: (2018)

Vacuolar proton-translocating ATPase is required for antifungal resistance and virulence of Candida glabrata
por: Minematsu, Asuka, et al.
Publicado: (2019)

Hyperacidification of Citrus fruits by a vacuolar proton-pumping P-ATPase complex
por: Strazzer, Pamela, et al.
Publicado: (2019)

Cancer with low cathepsin D levels is susceptible to vacuolar (H(+))‐ATPase inhibition
por: Kitazawa, Satoshi, et al.
Publicado: (2017)

Pharmacologic inhibition of vacuolar H+ ATPase reduces physiologic and oncogenic Notch signaling
por: Kobia, Francis, et al.
Publicado: (2013)

Vacuolar ATPase depletion contributes to dysregulation of endocytosis in bloodstream forms of Trypanosoma brucei
por: Xu, Zhi-Shen, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_bstq88rke0us6rvuso0d8vs41o